نتایج جستجو برای: sustained virologic response svr

تعداد نتایج: 1046149  

Journal: :iranian journal of virology 0
f zarepour blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran z sharifi blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran

background and aims: hepatitis c virus is one of the viral infections which is mainly transmitted by blood transfusion. patients with thalassaemia frequently need blood transfusion and are in danger of hcv infection. in most cases of infection (85%) the virus evades the immune system and establishes a chronic infection that may lead to cirrhosis and liver carcinoma. liver is the main site of hc...

Journal: :iranian journal of virology 0
f zarepour blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran z sharifi blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran

background and aims: hepatitis c virus is one of the viral infections transmitted by blood transfusion. patients with thalassaemia frequently need blood transfusion and are in danger of hcv infection. in most cases of infection (85%) the virus evades the immune system and establishes a chronic infection that may lead to cirrhosis and liver carcinoma. liver is the main site of hcv replication hc...

Ali Kabir, Hadi Ghofrani, Hossein Foroutan Pishbijary, Seyed Moayed Alavian, Shahram Mirmomen,

Introduction: The aim of this study is to assess the therapeutic efficacy and safety of a particular brand of IFN alpha (PDferon B®) in combination with ribavirin (RlBA) on Iranian patients with chronic hepatitis C (CHC). The addition of RIBA to the standard treatment with interferon (IFN) alpha led to an improvement in sustained virologic response (SVR) from less than 20% with IFN monother...

Journal: :medical journal of islamic republic of iran 0
seyed moayed alavian dept. ofgastoenterology, baqiyatallah university of medical sciences; the department of gastroenterology, imam khomeiniسازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (baqiyatallah university of medical sciences) hossein foroutan pishbijary dept. ofgastoenterology, baqiyatallah university of medical sciences; the department of gastroenterology, imam khomeiniسازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (baqiyatallah university of medical sciences) shahram mirmomen imam khomeini hospital, endoscopy ward, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) hadi ghofrani dept. ofgastoenterology, baqiyatallah university of medical sciences; the department of gastroenterology, imam khomeiniسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences) ali kabir dept. ofgastoenterology, baqiyatallah university of medical sciences; the department of gastroenterology, imam khomeiniسازمان اصلی تایید شده: دانشگاه علوم پزشکی بقیه الله (baqiyatallah university of medical sciences)

introduction: the aim of this study is to assess the therapeutic efficacy and safety of a particular brand of ifn alpha (pdferon b®) in combination with ribavirin (rlba) on iranian patients with chronic hepatitis c (chc). the addition of riba to the standard treatment with interferon (ifn) alpha led to an improvement in sustained virologic response (svr) from less than 20% with ifn monotherapy ...

Journal: :Gastroenterology 2010
Alexander J Thompson Andrew J Muir Mark S Sulkowski Dongliang Ge Jacques Fellay Kevin V Shianna Thomas Urban Nezam H Afdhal Ira M Jacobson Rafael Esteban Fred Poordad Eric J Lawitz Jonathan McCone Mitchell L Shiffman Greg W Galler William M Lee Robert Reindollar John W King Paul Y Kwo Reem H Ghalib Bradley Freilich Lisa M Nyberg Stefan Zeuzem Thierry Poynard David M Vock Karen S Pieper Keyur Patel Hans L Tillmann Stephanie Noviello Kenneth Koury Lisa D Pedicone Clifford A Brass Janice K Albrecht David B Goldstein John G McHutchison

BACKGROUND & AIMS We recently identified a polymorphism upstream of interleukin (IL)-28B to be associated with a 2-fold difference in sustained virologic response (SVR) rates to pegylated interferon-alfa and ribavirin therapy in a large cohort of treatment-naive, adherent patients with chronic hepatitis C virus genotype 1 (HCV-1) infection. We sought to confirm the polymorphism's clinical relev...

2013
Yidan Lu Anton Andonov David K. H. Wong

24 Hepatitis C (HCV) viremia is unusual (<5%) after successful treatment, defined as sustained 25 virologic response (SVR) or undetectable HCV PCR 12-24 weeks after therapy. We present a 26 case of late virologic relapse (de novo infection excluded by RNA sequencing) after SVR 27 followed by spontaneous viral clearance. 28

Journal: :Journal of clinical microbiology 2014
Yidan Lu Anton Andonov David K H Wong

Hepatitis C virus (HCV) viremia is unusual (<5%) after successful treatment, defined as sustained virologic response (SVR) or undetectable HCV PCR 12 to 24 weeks after therapy. We present a case of late virologic relapse (de novo infection was excluded by RNA sequencing) after SVR followed by spontaneous viral clearance.

2016
Robert Flisiak Joanna Pogorzelska Hanna Berak Andrzej Horban Iwona Orłowska Krzysztof Simon Ewelina Tuchendler Grzegorz Madej Anna Piekarska Maciej Jabłkowski Zbigniew Deroń Włodzimierz Mazur Marcin Kaczmarczyk Ewa Janczewska Arkadiusz Pisula Jacek Smykał Krzysztof Nowak Marek Matukiewicz Waldemar Halota Joanna Wernik Katarzyna Sikorska Iwona Mozer-Lisewska Błażej Rozpłochowski Aleksander Garlicki Krzysztof Tomasiewicz Joanna Krzowska-Firych Barbara Baka-Ćwierz Wiesław Kryczka Dorota Zarębska-Michaluk Iwona Olszok Anna Boroń-Kaczmarska Barbara Sobala-Szczygieł Bronisława Szlauer Bogumiła Korcz-Ondrzejek Jerzy Sieklucki Robert Pleśniak Agata Ruszała Barbara Postawa-Kłosińska Jolanta Citko Anna Lachowicz-Wawrzyniak Joanna Musialik Edyta Jezierska Witold Dobracki Beata Dobracka Jan Hałubiec Rafał Krygier Anna Strokowska Wojciech Chomczyk Krystyna Witczak-Malinowska

THE AIM OF THE STUDY Was to analyze the efficacy achieved with regimens available for chronic hepatitis C (CHC) in Poland between 2013 and 2016. MATERIAL AND METHODS Data were collected from 29 centers and included 6786 patients with available sustained virologic response (SVR) data between 1 January 2013 and 31 March 2016. RESULTS The sustained virologic response rate for genotypes (G) 1a,...

2014
Nobuhiro Harada Sumihito Tamura Yasuhiko Sugawara Junichi Togashi Takeaki Ishizawa Junichi Kaneko Taku Aoki Yoshihiro Sakamoto Kiyoshi Hasegawa Tomohiro Tanaka Noriyo Yamashiki Norihiro Kokudo

Single nucleotide polymorphisms of interleukin-28B (IL28B) rs8099917 are reported to be associated with virologic clearance in interferon-and ribavirin -based treatment for hepatitis C virus (HCV)-infected patients. We examined virologic response in accordance with IL28B polymorphisms in our living donor liver transplantation series under a preemptive interferon and RBV treatment approach. Adeq...

آقاصادقی, محمدرضا, دانشور, مهتاب, سادات, سید مهدی, مهمازی , ساناز,

Background and purpose: The standard of care treatment for infected patients with HCV is based on a combination of pegylated interferon alpha and ribavirin. Recently, the rs12979860 SNP polymorphism, located upstream of the interleukin 28B gene, was shown to be strongly associated with response to anti-HCV therapy. This study investigated the distribution of the (C/T) polymorphism with sust...

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