introduction: ifosfamide (ifo) is a potent drug that is used in cancer therapy. the major uses of ifo are: solid tumors especially, osteogenic sarcoma, other soft tissue sarcomas and hematologic malignancy, especially in lymphoma patients. the toxicity of ifo is very encompassing and includes: alopecia, nausea, vomiting, gastrointestinal, renal and neurological problems. neuropsychiatric toxici...

results anxiety, as the second most common reason of psychiatric disorders in cases of poisoning, with a prevalence of 12.1% in form of mild, 75.9% moderate and 12.1% severe, was confirmed among the participants of this study. conclusions the prevalence of anxiety among cases of poisoning with both drugs and chemicals are noticeably higher than general population. this fact strongly suggests th...

we aimed to compare acceptability of levonorgestrel with the yuzpe regimen among iranian women based on their side-effects and resulting changes in the amount and pattern of menses.five hundred twenty nine participants aged 15-49 having regular menses and one act of unprotected intercourse within 72 h were included in the double-blind, controlled trial in 2006-2007 and randomly assigned into ln...

introduction: patients referred to as having thalassemia major are usually those who come to medical attention in the first year of life and subsequently require regular transfusions to survive. those who present later or who seldom need transfusions are said to have thalassemia intermediahydroxyurea, an s-phase-specific and non-dna-hypomethylating chemotherapeutic agents is capable of inducing...

esfarzeh is a name used for two species of plantago genus, belonging to plantaginaceae family. in the iranian traditional medicine (itm) texts, esfarzeh is called bazreghatuna, and have different therapeutic effects including treatment of hoarseness of chest, pharynx, and tongue warm palpitation constipation caused by bile abdominal cramps gastric and intestinal ulcers arthralgia solid edema an...

multiple sclerosis (ms) is a chronic auto-immune disease. most therapeutic strategies for treatment of this disease direct immune modulation and control of inflammatory processes. first-line therapeutic agents showed moderate efficacy and frequent side-effects with moderate efficacy in trials. their parental administration and limited long-term adherence restrict their efficacy compared with se...

previous, intravenous immunoglobulin (ivig) has been used for treatment of patients with immunodeficiency. however, recent studies have shown that ivig is a suitable approach for treatment of inflammatory and autoimmune diseases. although the exact mechanism of ivig action is not well known, recent findings have demonstrated that ivig impacts on expression and function of fc receptors of immuno...

pain in icu patients should be managed effectively and safely. fentanyl and paracetamol are used frequently in icu. however experience using iv paracetamol in the setting of critically ill patients is limited. we evaluated the analgesic effect and adverse reactions of intravenous paracetamol compared to fentanyl in icu patients with mild to moderate pain. forty patients in a general icu were ra...

objective: this study sought to explore university of ghana business school diploma student's knowledge of contraceptives, types of contraceptives, attitudes towards contraceptive users, preference for contraceptives, benefits, and side-effects of contraceptives. materials and methods: data was conducted with three sets of focus group discussions. participants were systematically sampled from a...