background: progressions in science and technology have generated several methods for delaying preterm delivery and abortion; therefore, discovering an easy, non-invasive, practical, and non-expensive predictive factor can help us to perform preventive methods in healthy pregnant women, without any risk factors. objective: to indicate an appropriate index for predicting abortion in early pregna...

background and aims: some nanoparticles can be used in immunoassays to increase sensitivity. this study aimed to evaluate a novel nano-immunoassay based on bovine serum albumin nanoparticles (bsa nps). materials and methods: at first, the nanostructure was synthesized, and then applied as a tag in the nano-immunoassay. then the concentration of β-subunit of human chorionic gonadotropin (βhcg) i...

the purification of biomolecules is a necessary step in many biochemical researches. in this regard, developments of convenient, specific and low cost methods of purification are of particular interest. given the human hemoglobin (hb) affinity toward some charged carbohydrates, interaction of this molecule with human chorionic gonadotropin (hcg) which is a glycoprotein hormone containing sialic...

Ectopic secretion of beta-human chorionic gonadotropin is considered a poor prognostic marker in epithelial tumors. However, very few cases have been reported in sarcomas. We present the case of a 26-year-old female who presented with a metastatic osteosarcoma. She underwent usual testing prior to starting treatment and was found to have elevated levels of beta-human chorionic gonadotropin. As ...

OBJECTIVE To evaluate the relative importance of thyroid hormones and human chorionic gonadotropin in relation to the risk of gestational thyrotoxicosis in Saudi women living in Jeddah, Kingdom of Saudi Arabia. METHODS A prospective study was conducted on Saudi healthy pregnant women (N=406) at 12-15 weeks of gestation and compared with healthy non-pregnant controls (N=200). Maternal serum le...

A new commercially available chemiluminescence immunoassay for the quantitative measurement of human chorionic gonadotropin and its beta-subunit in serum was compared with the enzyme immunoassay used in our routine laboratory. Human chorionic gonadotropin was determined in serum from pregnant women, as well as from women with abortus imminens, suspected ectopic pregnancies or with molar pregnan...

routinely, a bolus of 5.000-10.000 iu human chorionic gonadotropin (hcg) is usedfor the final follicular maturation and ovulation as a standard method. hcg has thesame effect of luteinizing hormone (lh) with long half-life. it has the longlutheotrophic effect which increases the risk of ovarian hyper stimulation syndrome(ohss). recently, gonadotropin-releasing hormone agonist (gnrh-a) trigger h...

We report the case of a 22-year-old male who had a history of metastatic right testicular tumor successfully treated with chemotherapy and surgery. Twenty-one months after the initial treatment, the serum human chorionic gonadotropin started to increase gradually, but whole body imaging including the left testis revealed no abnormal finding except testicular microlithiasis. A biopsy of the left...

The current work aimed to study the effect of preeclampsia on maternal serum level of beta subunit of human chorionic gonadotropin and maternal plasma level of adenosine deaminase. Ninety pregnant women with gestational age 24 26 weeks were selected for this study, they were classified into three groups: group 1 consists of 30 women with normal pregnancy, group 2 consists of 30 patients with mi...

context maternal serum human chorionic gonadotropin (hcg) and alpha fetal protein (afp) were originally introduced to detect trisomy 21 and neural tube defects. however, in the absence of aneuploidy or neural tube defects, mid-trimester maternal serum hcg and/or maternal serum afp associated with adverse pregnancy outcomes. pregnancies with unexplained mid-trimester elevation in maternal serum ...