introduction: this study was performed to establish a complementary method to the diagnosis of complete hydatidiform mole and its differentiation from the other cases of gestational trophoblastic disease by measuring the total (alp) and placental alkaline phosphatase (plap) specific activity. materials and methods: serum and tissue extracts from 13 patients, 13 normal non-pregnant and 30 pregna...

the activity of mouse endometrial alkaline phosphatase after hyperstimulation and progesterone injection at the implantation time alkaline phosphatase (alp) of endometrium may play a critical function in the development and implantation of embryo. the aim of this study was to determine the localization of endometrial alp activity after hyperstimulation and progesterone injection. thirty adult f...

Alkaline phosphatase (ALP) activity was detected using bovine serum albumin (BSA)-functionalized manganese-doped zinc sulfide (Mn–ZnS) quantum dots (QDs), and the phosphate substrate vitamin-B 6 cofactor pyridoxal 5′-phosphate (PLP).

Osteosarcoma is an aggressive malignancy of the bone and an increase in serum alkaline phosphatase concentration has clinical prognostic value in both humans and canines. Increased serum alkaline phosphatase concentration at the time of diagnosis has been associated with poorer outcomes for osteosarcoma patients. The biology underlying this negative prognostic factor is poorly understood. Given...

Fractionation of serum alkaline phosphatase by either biochemical or electrophoretic techniques is often insufficient to determine the source of the elevated serum enzyme. In 31 unselected patients with high serum alkaline phosphatase a simultaneous determination of serum gamma glutamyl transpeptidase and urinary hydroxyproline excretion rates was performed, in addition to urea denaturation and...

To measure changes in bone alkaline phosphatase (EC 3.1.3.1) activity in serum as a function of duration of pregnancy, we adapted our existing alkaline phosphatase (ALP) isoenzyme assay (which has been used to measure bone, hepatic, and intestinal ALP activities in serum, in the absence of placental ALP) to allow quantification of individual ALP isoenzyme activities in the presence of placental...

Background: Diabetes mellitus, a group of metabolic disorder with multiple etiologies is characterized by chronic hyperglycaemia, induced deficiency insulin production and action. Prediabetes type hyperglycemia in which glycemic indices are higher than normal but lower the diabetes threshold. Objective: This study aims to assess impact bone markers (serum calcium, phosphorus alkaline phosphatas...

background: the present study was carried out on the human population of kashmir valley to evaluate the status of the biochemical parameters of infected population. materials and methods: blood samples were collected from 514 individuals, 298 (57.97%) males and 216 (42.02%) females, 187 (36.38%) were found sero-positive for human toxocariasis. results: alkaline phosphatase level was found highe...

Alkaline phosphatase (ALP) and bone-specific alkaline phosphatase (S-bone ALP) activities may serve as markers of the course and rate of bone healing after sustained fractures. The aim of this study was to examine whether the assessment of S-bone ALP as a biochemical parameter in the early posttraumatic phase may indicate the course of fracture healing. To date, the methods used to monitor the ...

Diagnosis Serum alkaline phosphatase (ALP) measurement: Measurement of serum ALP activity has been used as a screening test for HAC. However, the best way to use measurement of ALP activity may be as a means to rule out the diagnosis of HAC. The sensitivity of this laboratory test is high, as ALP is above normal in 90% of dogs with HAC. 2 However, the specificity is very low. Scottish terriers ...