Serum transferrin, estimated by total iron-binding capacity (TIBC), may be a marker of protein-energy wasting (PEW) in maintenance hemodialysis (MHD) patients. We hypothesized that low TIBC or its fall over time is associated with poor clinical outcomes. In 807 MHD patients in a prospective 5-year cohort, associations of TIBC and its changes over time with outcomes were examined after adjustmen...

The serum iron was determined in 60 normal subjects (38 males and 22 females) with a mean age of 32.0 and 36.2 years respectively. The plasma total iron-binding capacity (TIBC) was also determined in 54 of these subjects (32 males and 22 females). Serum iron and TIBC determinations were performed between 8.45 am and 9.15 am. The mean serum iron concentration is 138.3 +/- 4.3 mug/100 ml (SD +/- ...

OBJECTIVE To determine the diagnostic accuracy of serum iron and total iron binding capacity (TIBC) in detection of iron deficiency. STUDY DESIGN Descriptive, analytical study. PLACE AND DURATION OF STUDY Department of Chemical Pathology and Endocrinology, from January 2013 to October 2015. METHODOLOGY Data of 1,815 patients with results of serum iron, TIBC and ferritin from January 2013 ...

Because of the large quantities of venous blood required, assays of total iron-binding capacity (TIBC) and serum iron are often omitted in diagnostic tests involving small children. As an alternative to the conventional method of assessing TIBC, we developed a micromethod based on flameless atomic absorption spectrophotometry (flameless AAS). Additionally, the standard microproc#{233}dure for d...

We sought to determine if serum total iron-binding capacity (TIBC) is equivalent to serum transferrin (TRF) so that a low-cost colorimetric chemical assay for unsaturated iron-binding capacity (UIBC) could be substituted for a high-cost immunologic assay for TRF. Our study design included independent and blinded measurements of UIBC, serum iron, and TRF concentrations in human serum samples. Da...

iron concentration or UIBC value is below detectable limits, TIBC cannot be determined. In conclusion, TIBC values determined by DTIBC assay were strongly correlated with TRF concentrations. The slope of the regression line for the DTIBC values plotted against the TRF is consistent with the theoretical TIBC/ TRF ratio. TIBC values calculated from the sum of serum iron and UIBC were significantl...

Original Article Background & objectives: To assess the nutritional iron status and anemia prevalence in rural children of Warangal district, A.P. INDIA. Methods: We have studied serum iron, total iron-binding capacity (TIBC) relation ship in 50 rural children in the age group of 8-12 years. Results: As expected there was a highly significant increased levels of serum iron and a lower TIBC. The...

backgrounds and aims: thyroid hormones have a crucial physiological role to maintain balance of metabolism of body. thyroid hormones have an important role in metabolism and proliferation of blood cells. thyroid gland also has a vital influence on erythropoiesis by induction of erythropoietin secretion and proliferation of erythroid progenitors. in the present study, it was tried to evaluate th...

I evaluated a commercial electrochemical method (Environmental Science Associates), based on potentiostatic coulometry, for determining iron and total iron-binding capacity (TIBC). The method requires 25 and 100 microL of serum, respectively, for these measurements. Serum iron concentrations so determined in 99 normal volunteers satisfactorily correlated with those determined by the Iron Panel ...

Ferritin values for 250 selected sera were compared with values for iron, total iron-binding capacity (TIBC), and transferrin saturation, to assess the potential of the ferritin assay for the detection of latent iron deficiency. The specimens were grouped (50 in each group) according to their values for iron and TIBC. In Group 1 (low iron, high TIBC) the saturation and ferritin values both indi...