نتایج جستجو برای: scatchard
تعداد نتایج: 1284 فیلتر نتایج به سال:
Several types of widespread errors in performing Scatchard plot analysis resulting in fatal distortions of calculated affinities are surveyed more or less systematically. It appears that graphical analysis of non-linear Scathard plot “by eye” is almost impossible; and, moreover, results calculated by computer programs for affinity analysis often require additional "interpretation". Some of repo...
When we use Scatchard analysis for insulin receptor on intact cells, internalization of insulin may affect the Scatchard analysis. In this study, results from Scatchard analysis for insulin receptor on hepatocytes of streptozotocin (STZ)-induced diabetic rats were compared with those from association and dissociation studies and those from Scatchard analysis using hepatocyte membrane which does...
Nonlinear Scatchard plots are often found for agonist binding to G-protein-coupled receptors. Because there is clear evidence of receptor dimerization, these nonlinear Scatchard plots can reflect cooperativity on agonist binding to the two binding sites in the dimer. According to this, the "two-state dimer receptor model" has been recently derived. In this article, the performance of the model ...
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