microcerotermes diversus (silvestri) (isoptera: termitidae), an important wood pest in ahwaz (khuzestan, iran), causes serious economic damage to cellulosic products in buildings. to investigate the genetic diversity of this pest, 13 populations from different areas of khuzestan province as well as two samples from khark island and bandar abbas were collected. following dna extraction a fragmen...

The paper in the present issue of the APJCP by Mandal and his colleagues offers a disturbing contrast to generally positive conclusions of the recent special article by Breen et al (2001) on progress in cancer screening in the USA. The underlying differences in basic assumptions are of essential significance if we are to advocate national screening programs in Asia. A simple comparison points t...

Social Class and Serum Uric Acid M. G. Cook, M.B., and others; R. Finn, M.D. .......................... 232 Sudden Death after Exertion M. McCormack, M.B.; D. C. L. Savage, M.R.C.P. ......................... 232 Congenital Anomalies of the Vas Deferens R. E. B. Tagart, F.R.C.S...................233 Warning to Travellers to Tanzania G. H. Robb, M.R.C.P. 233 Exposure and Exhaustion G. A. Ballance...

Carfilzomib, an irreversible proteasome inhibitor, has a favorable safety profile and significant antitumor activity in patients with relapsed and refractory multiple myeloma (MM). Here we summarize the clinical pharmacokinetics (PK), metabolism, and drug-drug interaction (DDI) profile of carfilzomib. The PK of carfilzomib, infused over 2–10 minutes, was evaluated in patients with solid tumors ...

Posttranslational modification (PTM) of islet autoantigens can cause lack of central tolerance in type 1 diabetes (T1D). Tissue transglutaminase (tTG), involved in PTM of gluten antigens in celiac disease, creates negatively charged peptides favored by T1D-predisposing HLA-DQ molecules, offering an attractive candidate modifying islet autoantigens in T1D. The highly predisposing HLA-DQ8cis/tran...

There is evidence from epidemiological studies suggesting that increased consumption of cruciferous vegetables may protect against specific cancers more effectively than total fruit and vegetable intake. These beneficial effects are attributed to the glucosinolate breakdown products, isothiocyanates (ITC). Similarly, selenium (Se) consumption has also been inversely associated with cancer risk ...

The present study evaluates the acaricidal properties of crude ethanolic extract of Cassia fistula leaves for controlling Rhipicephalus (Boophilus) annulatus based on adult immersion test (AIT). The percentage of adult mortality, inhibition of fecundity and hatching of ova laid were studied at different concentrations of the extract ranging from 50 to 100 mg / ml. The results were compared usin...