SUMMARY  Hodgkin's disease has been known to medical practitioners for more than three centuries. The clinical and pathologic description of the disease published by Thomas. Hodgkin first in 183 2 when reported seven cases th-at he considered a new clinical entity.  The incident, clinical feature, histologic, procedure of evaluation and staging of Hodgkin's disease are presented briefly. Part...

This report is a brief presentation of one case of Oilier's disease. Ollier's disease (multiple enchondromata) patients have widespread involvement of the skeleton, especially the hands the lesions are detected because of bone pain or deformity. Virtually all cases have been sporadic. Roentgenographically, the lesions may be detectable in early infancy as clear, homogeneous, oval lesions w...

Crohn's disease (CD) is an inflammatory disease of the gastrointestinal tract (GIT) tract and can affect several parts of the digestive system. There is a relationship between impaired mucosal barrier in the GIT of inflammatory bowel disease patients and the role of bacteria such as Mycobacterium avium paratuberculosis in CD. Apart from different therapeutic approaches for treating CD, developm...

Alzheimer’s disease (AD) is a neurodegenerative disorder and the most common form of dementia. Almost 47 million people suffer from dementia worldwide. AD accounts for approximately 60%–80% of all dementia cases. Three major pathologies characterize the disease: senile plaques, neurofibrillary tangles and inflammation. We review the literature on events contributing to the inflammat...

background: parkinson’s disease (pd) is a progressive neurodegenerative disorder causing motor and non‑motor symptoms. the latter are common and include autonomic dysfunction, cognitive impairment, and sleep difficulties. many of the non‑motor aspects of pd such as sleep disturbance are more common and significantly affect the day‑to‑day activities of patients and their quality of life. the mos...

the peak age of onset of inflammatory bowel disease (ibd) is simultaneous with the peak reproductive years. patients have many concerns about the impact of ibd on fertility and pregnancy outcomes. the most important reason for voluntary childlessness is the fear of side effects from medications for ibd. decision making for medical therapy is a complex equation. it is important to summarize avai...

inflammatory bowel disease (ibd) is the term used for a group of diseases with yet unknown etiology, prevalence of which is increasing almost everywhere in the world. the disease was almost non-existent four decades ago in the east, including the middle-east, while now a days it is seen more and more. in addition to the increasing prevalence, our knowledge about its pathogenesis, clinical cours...

background: besides medical therapy, surgical interventions plays an important role in the treatment of inflammatory bowel disease (ibd), but they also involve complications and advantages. this study was undertaken to determine the characteristics and outcome of surgery in patients with ibd. â  methods: all the files of the patients admitted in nemazee and faghihi hospitals with the final diag...

ascites in the course of crohn's diseases is rare and is usually a sign of a concomitant malignancy, infection or thrombosis of portal or hepatic vein. herein, we reported on a 26-year-old man who was initially admitted with severe crohn's ileocolitis complicated by copious exudative ascites, abdominal pain and sever diarrhea. in our patient, we could not find any of the aforementioned conditio...

ulcerative colitis (uc) and crohn's disease (cd) are chronic inflammatory bowel diseases with uncertain etiology thought to be triggered by interactions between various environmental, genetic and immunologic factors. incidence rate of cd and uc is different in various geographic areas around the world, between 0.1-11 and 0.5-24.5 per 100,000 people for cd and uc, respectively. recent studies in...