نتایج جستجو برای: ros.

تعداد نتایج: 30099  

Journal: :iranian journal of public health 0
m negahdar m djalali h abtahi mr sadeghi t aghvami e javadi

experimental and epidemiological evidences implicate the involvement of oxygen derived radicals in the pathogenesis of cancer development. oxygen derived radicals are able to cause damage to membranes, mitochondria and macromolecules including proteins, lipids and dna. accumulation of dna damages has been suggested to contribute to carcinogenesis. it would, therefore, be advantageous to pinpoin...

Journal: :modares journal of medical sciences: pathobiology 2014
saeideh nouri mansoureh movahedin zohreh mazaheri

objective: oxidative stress as a consequence of aging can induce infertility in males. in this study, we have investigated the effects of aging on sperm parameters, intra-spermatic water soluble antioxidants, reactive oxygen species (ros), and in vitro blastocyst formation. methods: we chose 5 older nmri male mice (10-12 months) and 5 younger nmri male mice (2-3 months). sperm parameters, ros, ...

Journal: :iranian journal of allergy, asthma and immunology 0
mirshafiey abbas department of immunology, school of public health, tehran university of medical sciences, tehran, ir mohsenzadegan monireh department of immunology, school of public health, tehran university of medical sciences, tehran, ir

rheumatoid arthritis is a disease associated with painful joints that affects approximately 1% of the population worldwide, and for which no effective cure is available. it is characterized by chronic joint inflammation and variable degrees of bone and cartilage erosion. oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis. reactive oxygen species (ros) are produc...

Journal: :iranian journal of pharmaceutical research 0
mehrdad faizi school of pharmacy, shahid beheshti university of medical sciences, tehran, iran ahmad salimi school of pharmacy, shahid beheshti university of medical sciences, tehran, iran motahareh rasulzadeh school of pharmacy, shahid beheshti university of medical sciences, tehran, iran parvaneh naserzadeh school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. jalal pourahmad school of pharmacy, shahid beheshti university of medical sciences, tehran, iran.

schizophrenia is a chronic and often debilitating illness which affects about 1% of the world population. some reagents have been used to simulate schizophrenic disorders in laboratory animals, such as amphetamine and ketamine. previous studies have suggested that reactive oxygen species (ros) production, reduced levels of atp, mitochondrial dysfunction and apoptosis are involved in the pathoph...

Journal: :iranian biomedical journal 0
عباس ابراهیمی کلان abbas ebrahimi-kalan مهریار حبیبی رودکنار mehryar habibi roudkenar راحله حلبیان raheleh halabian پیمان بروکی میلان peiman broki milan آرمین زرین تن armin zarrintan آمنه محمدی روشنده amaneh mohammadi roushandeh

background: it is proved that testis is sensitive to electromagnetic field (emf) and its damage results in infertility. exposure to emf induces reactive oxygen species production and affects on anti-oxidants defense mechanisms. metallothionein (mt) is a name for a group of low molecular weight (6-7 kda), sulfhydryl rich proteins. expression of mt1 and mt2 genes in testis tissue after emf exposu...

Journal: :iranian journal of pharmaceutical sciences 0
alama badrul department of pharmacy, atish dipankar university of science and technology, dhaka, bangladesh haque ekramul department of pharmacy, brac university, dhaka, bangladesh

the crude methanolic extract of the seeds of celastrus paniculatus along with its organic soluble fractions were tested for their possible antioxidant and anti-alzheirmer (ad) activity. the extracts showed prominent dpph free radical scavenging activity, inhibiting activity of authentic peroxynitrite (onoo-) and inhibition of total reactive oxygen species (ros) generation. in dpph radical scave...

Journal: :Physiological reviews 2014
Dmitry B Zorov Magdalena Juhaszova Steven J Sollott

Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of potentially damaging levels of reactive oxygen species (ROS), Ca(2+), etc., which must be normalized. Evidence suggests that brief mitochondrial permeability transition pore (mPTP) openings play an important physiological role maintaining healthy mitochondria homeostasis. Adaptive and maladaptive responses to r...

Journal: :international journal of fertility and sterility 0
mohammad eid hammadeh alixides filippos a mohammed faiz hamad

spermatozoa generate reactive oxygen species (ros) in physiological amounts which play a role in sperm functions during sperm capacitation acrosome reaction (ar) and oocyte fusion. in addition damaged sperm are likely to be the source of ros. the most important ros produced by human sperm are hydrogen peroxide superoxide anion and hydroxyl radicals. besides human seminal plasma and sperm posses...

Journal: :Journal of Extracellular Vesicles 2019

Journal: :Oxidative Medicine and Cellular Longevity 2016

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