Like the biological clock in the body, replication of each cell type (even different cells of the same organism) follows a timing program. Abnormal function of this timer could be an alarm for a disease like cancer. DNA replication starts from a specific point on the chromosome that is called the origin of replication. In contrast to prokaryotes in which DNA replication starts from a single ...

toxoplasmosis is a protozoal infection caused by toxoplasma gondii. toxoplasmosis produce severe damage in patients who are immunosuppresed. in those who are immunosupressed, latent infection can be reactivated resulting in acute disseminating disease. betamethasone is a synthetic glycocorticoid, used as an anti-inflamatory and immunosuppressant in a wide variety of disorders.the aim of this st...

data grids support access to widely distributed storage for large numbers of users accessing potentially many files. to enhance access time, replication at nearby sites may be used. data replication, a technique much investigated bydata grid researchers in past years creates multiple replicas offile and places them in conventional locations to shorten fileaccess times. one of the problems in da...

SRC kinases and PKR are intracellular protein kinases, which play key roles in intracellular viral replication. In this research, the effect of SRC kinase inhibition and PKR activation and inhibition on replication of coxsakievirus (CVB3), an entrovirus of the family picornaviridae – causative agents of fatal myocarditis, was studied. Vero and Hela cells were cultured and infected with CVB3 in ...

objective: in this paper, we have introduced topoisomerase inhibitors, mechanism of action and types of them. dna topoisomerases are ubiquitous enzymes that catalyze essential enzymes to solve the topological problems accompanying key nuclear processes such as dna replication, transcription, repair and chromatin assembly by introducing temporary single or double strand breaks in the dna. result...

abstract— data grids are an important branch of gird computing which provide mechanisms for the management of large volumes of distributed data. energy efficiency has recently emerged as a hot topic in large distributed systems. the development of computing systems is traditionally focused on performance improvements driven by the demand of client's applications in scientific and business ...

conclusions after seven consecutive passages of both cell cultures, the h9n2 virus showed similar antigenicity, also no change on viral titer level and virus replication behavior in adaptation was found. the results highlighted the use of a549 cells for efficient virus isolation. results the influenza virus infectivity was not significant difference in these cells in the presence of trypsin. th...

As grow as the data-intensive applications in cloud computing day after day, data popularity in this environment becomes critical and important. Hence to improve data availability and efficient accesses to popular data, replication algorithms are now widely used in distributed systems. However, most of them only replicate the static number of replicas on some requested chosen sites and it is ob...

SRC kinases and PKR are intracellular protein kinases, which play key roles in intracellular viral replication. In this research, the effect of SRC kinase inhibition and PKR activation and inhibition on replication of coxsakievirus (CVB3), an entrovirus of the family picornaviridae – causative agents of fatal myocarditis, was studied. Vero and Hela cells were cultured and infected with CVB3 in ...