Nitric oxide (NO) is implicated as an important mediator of, or intermediary in, inflammation, immunity and neurotransmission. In the kidney, NO is involved in haemodynamic regulation, control of vascular tone and tubular function. Formation of oxygen-derived free radicals (OFR) have been documented in renal ischaemiareperfusion before. In this study, we investigated the significance of NO form...

Renal allograft thrombosis may be responsible for 2–7% of early allograft losses in adults [1] and up to 35% in children [2]. The North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) reported that graft thrombosis represented the main cause of graft failure in the first year. Most cases of renal allograft thrombosis occur early in the postoperative period with a peak incidence ...

Background Endothelium-derived C-type natriuretic peptide (CNP) possesses cytoprotective and anti-atherogenic functions that regulate vascular tone and smooth-muscle relaxation and might be key in protecting against ischaemiareperfusion injury [1]. The finding that many of the vasoprotective effects of CNP are mediated by the natriuretic peptide receptor type-C (NPR-C) suggests that this recept...

conclusions the patient underwent surgery applying a midline incision. the left kidney showed a lump pattern embedded in lower pole of the right kidney. left sided nephrectomy was performed while temporary right renal artery was clamped temporarily. histopathological evaluation revealed clear cell carcinoma with severe nuclear atypia (fuhrman grade 4/4). however, local recurrence was not detect...

background: atherosclerotic renal artery stenosis (aras) remains underdiagnosed due to its nonspecific demonstrations. we aimed to both estimate the frequency of aras in high-risk non-selected patients undergoing simultaneous coronary and renal catheterization and possibly identify a predictive model for aras using baseline clinical, laboratory, and coronary angiographic variables. methods: the...

introduction: osteodystrophy is one of the long term complications of chronic renal failure and is expressed in two formslow turn over and high turn over. it is an important cause of morbidity in patients with renal failure and if diagnosed and managed properly, many problems of these patients can be resolved. in this study we evaluated the prevalence of hyperparathyroidism in hemodialysis pati...