background & aim: regional odonto dysplasia (rod) is an unusual nonhereditary of teeth with significantly clinical and radiographic features. affected teeth usually remain unerupted or semi-erupted with a discolaration and irregular shape. radiographically these teeth have a large pulp chamber and thin layer of enamel and dentin with similar density. this article is introducing a female patient...

© 2011 The Authors. doi: 10.2340/00015555-1028 Journal Compilation © 2011 Acta Dermato-Venereologica. ISSN 0001-5555 WNT10A is a member of the wingless signalling pathway that has a fundamental role in skin and appendageal morphogenesis (1). Moreover, naturally occurring WNT10A gene mutations have been identified in the autosomal recessive human ectodermal dysplasia syndromes odonto-onycho-derm...

Objective: This study used published studies to assess the survival rate of dental implants placed in patients with bone dysplasia maxillofacial region.Material and methods: An electronic search without a specified date range was performed using MEDLINE, PubMed, EMBASE, Web Science, Cochrane databases. No gender or age restrictions were applied.Results: Eighteen publications found that met stud...

BACKGROUND Odonto-onycho-dermal dysplasia (OODD) is a rare form of ectodermal dysplasia characterized by severe oligodontia, onychodysplasia, palmoplantar hyperkeratosis, dry skin, hypotrichosis, and hyperhidrosis of the palms and soles. The ectodermal dysplasias resulting from biallelic mutations in the WNT10A gene result in highly variable phenotypes, ranging from isolated tooth agenesis to O...

Mutations in the WNT10A gene were first detected in the rare syndrome odonto-onycho-dermal dysplasia (OODD, OMIM257980) but have now also been found to cause about 35-50% of selective tooth agenesis (STHAG4, OMIM150400), a common disorder that mostly affects the permanent dentition. In our random sample of tooth agenesis patients, 40% had at least one mutation in the WNT10A gene. The WNT10A Phe...