نتایج جستجو برای: recombinant tissue plasminogen activator (rtpa).

تعداد نتایج: 1042975  

Journal: :medical journal of islamic republic of iran 0
masoud mehrpour department of neurology and stroke center, firoozgar general hospital, iran university of medical sciences, tehran, iran. salameh taghipour department of neurology and stroke center, firoozgar general hospital, iran university of medical sciences, tehran, iran. sahar abdollahi department of neurology and stroke center, firoozgar general hospital, iran university of medical sciences, tehran, iran. fatemeh oliaee department of neurology and stroke center, firoozgar general hospital, iran university of medical sciences, tehran, iran. azin goran department of neurology and stroke center, firoozgar general hospital, iran university of medical sciences, tehran, iran. mohamadreza motamed department of neurology and stroke center, firoozgar general hospital, iran university of medical sciences, tehran, iran.

background: firoozgar comprehensive stroke center started up as the first organized care unit in the country in 2014; this study was performed to investigate quality indicators such as reduction in mortality, morbidity and hospital stay.   methods: two groups of ischemic stroke patients were compared. the first group had been admitted in general neurology ward (non-stroke unit patients) and the...

2016
Maria Khan

Submit Manuscript | http://medcraveonline.com Abbreviations: UAE: United Arab Emirates; NINDS rtPA: Neurological Disorders and Stroke recombinant tissue plasminogen activator; tPA: tissue Plasminogen Activator; CT: Computerized Tomography; mRS: modified Rankin Scale; TOAST: Trial of Org 10172 in Acute Stroke Treatment criteria; NIHSS: National Institute of Health Stroke Scale; SPSS: Statistical...

Journal: :Chest 1992
M R Jackson G P Clagett

Abbreviations: ACD 5 absolute claudication distance; CI 5 confidence interval; INR 5 international normalized ratio; LMWH 5 low-molecular-weight heparin; MI 5 myocardial infarction; NASCET 5 North American Symptomatic Carotid Endarterectomy Trial; PGE1 5 prostaglandin E1; PGI2 5 prostaglandin I2; PTFE 5 polytetrafluoroethylene; rtPA 5 recombinant tissue plasminogen activator; tPA 5 tissue plasm...

2015
J.E. Tomlinson E. Byrne N. Pusterla K. Gary Magdesian H.G. Hilton B. McGorum E. Davis A. Schoster L. Arroyo B. Dunkel H. Carslake R.C. Boston A.L. Johnson

BACKGROUND Information about treatment protocols, adverse effects and outcomes with intrapleural recombinant tissue plasminogen activator (rTPA) use in horses with fibrinous pleuropneumonia is limited. HYPOTHESIS/OBJECTIVES Describe factors that contribute to clinical response and survival of horses treated with rTPA intrapleurally. ANIMALS Horses with bacterial pneumonia and fibrinous pleu...

Journal: :Stroke 2013
Pooja Khatri Marie-Luise Mono

M ore than half of ischemic stroke patients who are treated with IV recombinant tissue-type plasminogen activator (rtPA) remain disabled at 3 months. The reasons are many. The IV rtPA rate of recanalizing occluded arteries is not as high as we would like, especially for large arterial occlusions, which are opened only 30% to 40% of the time. 3–6 When rtPA does effectively lyse a thrombus, it is...

2014
Zhen Jing Shijun Zhang Jingjing Tang Anding Xu Yiwen Ruan Li'an Huang

KEY CLINICAL MESSAGE We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rtPA) thrombolysis even though there were no detectable lesions on diffusion-weighted imaging (DWI). DWI is very sensitive for diagnosing hyperacute ischemic stroke, and rtPA thrombolysis is the ...

Journal: :Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2014
Sébastien Lenglet Fabrizio Montecucco Adam Denes Graham Coutts Emmanuel Pinteaux François Mach Karl Schaller Yvan Gasche Jean-Christophe Copin

The effect of recombinant human tissue plasminogen activator (rtPA) on neuroinflammation after stroke remains largely unknown. Here, we tested the effect of rtPA on expression of cellular adhesion molecules, chemokines, and cytokines, and compared those with levels of inflammatory cell recruitment, brain injury, and mortality over 3 days after transient middle cerebral artery occlusion (MCAO) i...

Journal: :iranian journal of neurology 0
masoud mehrpour assistant professor, department of neurology and firoozgar hospital, tehran university of medical sciences, tehran, iran. mohammad reza motamed health policy research center, shiraz university of medical sciences, shiraz, iran mahboubeh aghaei health policy research center, shiraz university of medical sciences, shiraz, iran zahra badi research center for traditional medicine and history of medicine and department of neurology, shiraz university of medical sciences, shiraz, iran

stroke is an important cause of disability and death worldwide, with the majority of strokes occurring in older people. thrombolysis with recombinant tissue plasminogen activator (r-tpa) is the approved treatment for acute ischemic stroke. a major concern of physicians, who treat acute ischemic stroke with recombinant tissue plasminogen activator (r-tpa,) is the risk of intracerebral hemorrhage...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2010
William M Armstead John Riley J Willis Kiessling Douglas B Cines Abd Al-Roof Higazi

The sole FDA-approved treatment for acute stroke is recombinant tissue-type plasminogen activator (rtPA). However, rtPA aggravates the impairment of cerebrovasodilation induced by global hypoxia/ischemia; this impairment is attenuated by the preinjury treatment with the plasminogen activator inhibitor derivative EEIIMD. MAPK (a family of kinases, p38, and JNK) is upregulated after cerebral isch...

Journal: :iranian journal of neurology 0
mohammad reza motamed department of neurology, school of medicine, iran university of medical sciences, tehran, iran fereshteh nasiri department of neurology, school of medicine, iran university of medical sciences, tehran, iran seyed mohammad fereshtehnejad care sciences, and society (nvs), karolinska institute and department of neurobiology, stockholm, sweden and firoozgar clinical research development center, firoozgar hospital, iran university of medical sciences; tehran, iran masoud mehrpour firoozgar clinical research development center and department of neurology, school of medicine, firoozgar hospital, iran university of medical sciences; tehran, iran babak zamani department of neurology, school of medicine, iran university of medical sciences, tehran, iran bahram haghi-ashtiani department of neurology, school of medicine, iran university of medical sciences, tehran, iran

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