نتایج جستجو برای: receptor dependent breast cancer cells (mc4
تعداد نتایج: 2978229 فیلتر نتایج به سال:
the aim of this study was assessing the adjuvant therapy of exercise on cytokines balance in mice with breast cancer tumor. twenty female balb/c mice were randomly assigned to experimental and control groups. after orientation in the environment, estrogen-receptor dependent breast cancer cells (mc4-l2) were injected to them and experimental group performed endurance training 5 day in week for 6...
objective(s):breast cancer is an important leading cause of death from cancer. stathmin and tau proteins are regulators of cell motility, and their overexpression is associated with the progression and bad prognosis of breast cancer. memantine, an n-methyl-d-aspartate (nmda) receptor antagonist, is the potential inhibitor of tau protein in neurons. this study determines the effect of memantine ...
Objective(s):Breast cancer is an important leading cause of death from cancer. Stathmin and tau proteins are regulators of cell motility, and their overexpression is associated with the progression and bad prognosis of breast cancer. Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is the potential inhibitor of tau protein in neurons. This study determines the effect of memantine ...
Background and Objectives: Breast cancer is a major health concern in women, but it seems that exercise plays an important role in controlling it. Therefore, the aim of the present study was to examine the effects of six weeks of aerobic training on the tumor volume and oncostatin-M serum level in mice with breast cancer. Materials and Methods: This research was an experimental...
background: breast cancer is the most common cause of cancer in women. this tumor is hormone dependent tumor and oncologists use estrogen receptor (er), progesterone receptor (pr) and her2 for treatment of this malignancy. androgens like testosterone and their receptors (ar) have a role in the pathophysiology of breast cancer but their clinical values are not clear. method: ar expression was ev...
Introduction: Breast cancer is the most common cancer and the first cause of cancer-related death in women worldwide. Although admirable achievements have been made in finding new therapeutic interventions, introducing efficient approaches with the least side effect is still undoubtedly demanded. Exposure to extremely-low frequency electromagnetic field (ELF-EMF) with specific parameters of fre...
Background & Aims: Breast cancer is the most common cancer in women. Nearly 50% of breast cancers are dependent to sex hormones, and the effects of these hormones are mediated by their binding to specific receptors. Also p53 protein is mutated in about half of cancers including breast cancer and high level of p53 protein is a common feature of many human malignant cancers. Given that T47D cell...
background : breast cancer is one of the most frequent malignancies among iranian women. triple-negative breast cancer (tnbc) is referred to a type of breast cancer which three biomarkers of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 (her2), are negative. materials and methods: in this case control study, immunohistopathologic data of patients with tn...
psa is a 33-kda serine protease that is produced predominantly by prostate epithelium. however, it has been shown that about 30-40% of female breast tumors produce psa and its production is associated with the presence of estrogen and progesterone receptors. we have now developed a new tissue culture system to study psa production in breast cancer and its association with prognostic factors suc...
background and objective: determination of hormone receptor status in the management of breast cancer is well-established. the aim of this study was to evaluate the frequency of androgen receptor (ar) expression in invasive ductal carcinoma of breast. materials and methods: for this purpose, 55 cases of invasive ductal breast carcinoma were examined using a monoclonal antibody against ar on for...
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