نتایج جستجو برای: rat Corpus cavernosum

تعداد نتایج: 341323  

Journal: :iranian journal of pharmaceutical sciences 0
farzaneh boroumand department of biostatistics, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, iran alireza akbarzade baghban department of biostatistics, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, iran farid zayeri department of biostatistics, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, iran hediye faghir ghanesefat department of pharmacology, faculty of medicine, tehran university of medical sciences, tehran, iran

ignoring two main characteristics of the concentration-response data, correlation between observations and presence of outliers, may lead to misleading results. therefore the special method should be considered. in this paper in to examine the effect of phenylephrine in rat corpus cavernosum, outlier robust nonlinear mixed estimation is used. in this study, eight different doses of phenylephrin...

Ignoring two main characteristics of the concentration-response data, correlation between observations and presence of outliers, may lead to misleading results. Therefore the special method should be considered. In this paper in to examine the effect of phenylephrine in rat Corpus cavernosum, outlier robust nonlinear mixed estimation is used. in this study, eight different doses of phenylephrin...

2014
Jun Sik Lee In Sang Hwang Hyun-Suk Lee Mi Eun Kim Young-Woo Seo Kwangsung Park

The vascular wall resident progenitor cells seem to serve as a local reservoir of cells for vascular repair. It was hypothesized that the corpus cavernosum may contain vascular wall endothelial progenitor cells (EPCs). In this study, we investigated the identification and localization of EPCs in the corpus cavernosum in a rat model. Adult male Sprague-Dawley rats were used to isolate EPCs from ...

احمدرضا دهپور, , حامد صادقی‌پور, , مهدی قاسمی, ,

Background: Relaxation of the corpus cavernosum plays a major role in penile erection. Nitric oxide (NO) is known to be the most important factor mediating relaxation of corpus cavernosum, which is mainly derived from nonadrenergic noncholinergic (NANC) nerves. The aim of the present study was to investigate the effect of biliary cirrhosis on nonadrenergic noncholinergic (NANC)-mediated relaxat...

Journal: :American journal of physiology. Heart and circulatory physiology 2007
Andrey C da Costa Gonçalves Romulo Leite Rodrigo A Fraga-Silva Sergio V Pinheiro Augusto B Reis Fernando M Reis Rhian M Touyz R Clinton Webb Natalia Alenina Michael Bader Robson A S Santos

The vasodilator/antiproliferative peptide angiotensin-(1-7) [ANG-(1-7)] is released into the corpus cavernosum sinuses, but its role in erectile function has yet to be defined. In this study, we sought to determine whether ANG-(1-7) and its receptor Mas play a role in erectile function. The ANG-(1-7) receptor Mas was immunolocalized in rat corpus cavernosum by confocal microscopy. Infusion of A...

Journal: :The Journal of urology 2000
A C Pinheiro W S Costa L E Cardoso F J Sampaio

PURPOSE The corpus cavernosum smooth muscle and extracellular matrix are essential for normal penile erection and are implicated in erectile dysfunction. Although investigations of these issues have used the rat corpus cavernosum, organization of its components is to date not well known. We characterized and quantified the smooth muscle cells and the main extracellular matrix components of the ...

Journal: :Journal of morphology 2000
D A Kelly

The baculum is a nonappendicular bone found in the glans tissue of members of five orders of mammals. Its function during copulation is unknown. Anatomical examination of the baculum and corpus cavernosum in the Norway rat (Rattus norvegicus) shows that the two structures are connected by a layer of fibrocartilage, and that the distal tip of the corpus cavernosum swells during erection to surro...

Journal: :Journal of embryology and experimental morphology 1986
R Murakami T Mizuno

The penis of adult rats comprises the corpus cavernosum penis and the proximal and distal segments of os penis which are situated proximal-distally in this order. Androgens are necessary for the phenotypic differentiation of these tissues. In the present study, genital tubercular mesenchyme of foetal rats was recombined with or without homologous or heterologous epithelia and transplanted benea...

2012
Hong-Geun Oh Hak-Yong Lee Jung-Hoon Kim Young-Rye Kang Dea-In Moon Min-Young Seo Hyang-Im Back Sun-Young Kim Mi-Ra Oh Soo-Hyun Park Min-Gul Kim Ji-Young Jeon Sook-Jeong Shin Kang-Sun Ryu Soo-Wan Chae Okjin Kim Jong-Kwan Park

Erectile dysfunction (ED) is a highly prevalent disorder that affects millions of men worldwide. ED is now considered an early manifestation of atherosclerosis, and consequently, a precursor of systemic vascular disease. This study was designed to investigate the effects of male silkworm pupa powder (SWP) on the levels of nitric oxide synthase (NOS) expression, nitrite, and glutathione (GSH); l...

2016
Yuji Hotta Naoya Ieda Ayako Fukamoto Tomoya Kataoka Yoshihiro Kawade Yasuhiro Maeda Hidehiko Nakagawa Kazunori Kimura

PURPOSE To investigate whether relaxation of the rat penile corpus cavernosum could be controlled with NOBL-1, a novel, light-controllable nitric oxide (NO) releaser. MATERIALS AND METHODS Fifteen-week-old male Wistar-ST rats were used. The penile corpus cavernosum was prepared and used in an isometric tension study. After noradrenaline (10(-5) M) achieved precontraction, the penile corpus ca...

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