The development and characterization of effective anticancer drugs against colorectal cancer (CRC) is of urgent need since it is the second most common cause of cancer death. The study was designed to evaluate the effects of two IGF-1R antagonists, MK-0646, a recombinant fully humanized monoclonal antibody and OSI-906, a small molecule tyrosine kinase inhibitor on CRC cells. Xenograft study was...

Abstract Introduction Poor sleep quality is prevalent among college students and has a significant impact on their daily activities. Further, are under extreme pressure to excel in an academic, occupational social context, psychological distress often exacerbate quality. This study aimed examine relationships between stress undergraduate students. Methods Baseline data were obtained from who co...