Methods for determining inter-spin distances between nitroxide spin labels from dipolar couplings in the intermediate range (r12≈1.1-2 nm) by CW-EPR are addressed. For nitroxide powder patterns, the assumption of unlike spins is a better approximation than assuming strong coupling between like spins. Methods that determine the average splitting in dipolar deconvolutions yield the mean value 〈1/...

Music is often discussed to be emotional because it reflects expressive movements in audible form. Thus, a valid approach to measure musical emotion could be to assess movement stimulated by music. In two experiments we evaluated the discriminative power of mobile-device generated acceleration data produced by free movement during music listening for the prediction of ratings on the Geneva Emot...

RNA aptamers against bovine prion protein (bPrP) were obtained, most of the obtained aptamers being found to contain the r(GGAGGAGGAGGA) (R12) sequence. Then, it was revealed that R12 binds to both bPrP and its beta-isoform with high affinity. Here, we present the structure of R12. This is the first report on the structure of an RNA aptamer against prion protein. R12 forms an intramolecular par...

This file provide the detailed steps for obtaining the bounds on R1, R2 via the obtained results on (R1c, R1p, R2c, R2p). The rate pair (R1c, R1p, R2c, R2p) is achievable if it satisfies following inequalities. R1c ≤ rank(U 1 H11V21) (1) R1p ≤ m1 − r21 (2) R2c ≤ r12 (3) R1c +R1p ≤ r11 (4) R1c +R2c ≤ r12 + rank(U 10H11V21) (5) R1p +R2c ≤ r12 + rank(U 10H11V20) (6) R1c +R1p +R2c ≤ n1 (7) R2c ≤ ra...

Tumor suppressor protein p53 plays important roles in initiating cell cycle arrest and promoting tumor cell apoptosis. Previous studies have shown that p53 is either mutated or defective in approximately 50% of human cancers; therefore restoring normal p53 activity in cancer cells might be an effective anticancer therapeutic approach. Herein, we designed a chimeric p53 protein flanked with the ...

The taxonomic positions of two gamma- and UV-ray-resistant strains isolated from radiation-polluted soil in north-west China were determined in a polyphasic study. The organisms, designated R12(T) and R13(T), were Gram-stain-positive, non-spore-forming cocci, which contained MK-8 as the major respiratory quinone and C(16 : 1)omega7c and C(16 : 0) as major fatty acids. The cell walls of strains ...

The performance of the [2]S and [2]R12 universal perturbative corrections that account for oneand many-body basis set errors of singleand multiconfiguration electronic structure methods is assessed. A new formulation of the [2]R12 methods is used in which only strongly occupied orbitals are correlated, making the approach more amenable for larger computations. Three model problems are considere...

We calculate exactly the functional determinant for fermions in fundamental representation of SU(2) in the background of periodic instanton with non-trivial value of the Polyakov line at spatial infinity. The determinant depends on the value of the holonomy v, the temperature, and the parameter r12, which at large values can be treated as separation between the Bogomolny–Prasad– Sommerfeld mono...

Limited studies have compared BIM’s impacts on project performance via business types, working experience, and locations. A survey was conducted results found that (1) BIM helped with the early detection of design errors (R1), pre-construction RFIs (R2), number repeat customers (R12), but negatively affected other 9 indicators (R3~R11); (2) for R1/R2/R12, contractors, international projects, st...

Oneand two-body densities in position space have been calculated for the atomic beryllium isoelectronic series starting from explicitly correlated multideterminant wave functions. The effects of electronic correlations have been systematically studied by comparing the correlated results with the corresponding Hartree–Fock ones. Some expectation values such as ^d(r)&, ^r& , ^d(r12)& , ^r12 n &, ...