نتایج جستجو برای: proprotein convertase subtilisin/kexin type 9

تعداد نتایج: 1753151  

Journal: :iranian red crescent medical journal 0
hooshang zaimkohan department of medical genetics, faculty of medicine, tehran university of medical sciences, tehran, ir iran mohammad keramatipour department of medical genetics, faculty of medicine, tehran university of medical sciences, tehran, ir iran seyed reza mirhafez metabolic syndrome research center, school of medicine, mashhad university of medical sciences, mashhad, iran javad tavakkoly-bazzaz department of medical genetics, faculty of medicine, tehran university of medical sciences, tehran, ir iran azadeh tahooni department of internal medicine, school of medicine, iran university of medical sciences, tehran, ir iran mohammad piryaei department of medical genetics, school of medicine, shahid beheshti university of medical sciences, tehran, ir iran

materials and methods genotyping of the mia3 gene was undertaken using taqman real-time pcr in all subjects. anthropometric and biochemical features, including hdl, ldl, and tg were assessed in all subjects. results the cad patients had significantly (p < 0.05) higher bmi and significantly higher levels of tg, ldl, sbp, and dbp, while the level of hdl was lower compared to that of the control g...

Journal: : 2021

Literature data on the pathogenesis of atherosclerosis, use statins, ezetimibe and inhibitors subtilisin / kexin type 9 proprotein convertase monoclonal antibodies (PCSK9) in prevention treatment cardiovascular diseases have been presented.Objective - to systematize current effectiveness lipid-lowering therapy diseases.Conclusion. To date, role dyslipidemia inflammation PCSK9 established.

Journal: :Circulation research 2014
Martin Maeng Bjørklund Anne Kruse Hollensen Mette Kallestrup Hagensen Frederik Dagnaes-Hansen Christina Christoffersen Jacob Giehm Mikkelsen Jacob Fog Bentzon

RATIONALE Atherosclerosis can be achieved in animals by germline genetic engineering, leading to hypercholesterolemia, but such models are constrained to few species and strains, and they are difficult to combine with other powerful techniques involving genetic manipulation or variation. OBJECTIVE To develop a method for induction of atherosclerosis without germline genetic engineering. MET...

Journal: :P & T : a peer-reviewed journal for formulary management 2017
Walter Alexander

We report on selected research presented at the ACC 66th Annual Scientific Session and Expo, including sessions on proprotein convertase subtilisin/kexin type 9 inhibitors, anti-Xa anticoagulants, and a direct thrombin inhibitor.

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