background dermatophytes are a group of keratinophilic fungi worldwide, which can infect the skin, hair and nails of humans and animals. this genus includes several species that present different features of dermatophytosis. although, laboratory diagnosis of dermatophytes is based on direct microscopy, biochemical tests and culture, these manners are expensive, time consuming and need skilled s...

conclusions il6 and il8 gene polymorphisms have no role in nash pathogenesis and liver fibrosis process, but presence of the a/a genotype in the il8 gene is associated with disease progression. patients and methods consecutive patients with biopsy proven nash and age- and gender-matched healthy individuals with normal liver function tests and normal ultrasonography were enrolled in the study. h...

background: polycystic ovary syndrome (pcos) is a complex disease having both genetic and environmental components and candidate genes on obesity and insulin metabolism have been hypothesized to be involved in its etiology. objective: we examined the possible association of adiponectin and insulin receptor gene polymorphisms with pcos. materials and methods: a total of 186 women with pcos using...

angiotensin converting enzyme (ace; omim: 106180) has an important role in the conversion of angiotensin i to angiotensin ii and degradation of bradykinin. genetic polymorphism i/d (rs4646994) in the gene encoding ace has been well defined. to get more insight into the genetic structure of iranian populations, the distribution of the ace i/d polymorphism among iranians was compared with each ot...

conclusions our findings indicated that mdm2 40-bp ins/del polymorphism was not associated with all in our iranian population. further studies with larger sample sizes and diverse ethnicities are required to verify our findings. background the human murine double minute 2 (mdm2), an oncoprotein, is the major negative regulator of p53. objectives the purpose of this study was to evaluate the imp...

introduction: one factor known to cause thrombophilia in women with unexplained recurrent spontaneous abortion (rsa) is c677t polymorphism of methylenetetrahydrofolate reductase gene. this study aimed to determine the association between rsa and mthfr c677t polymorphism in iranian patients. methods: in this case-control study, 30 patients with previous history of two or more consecutive unexpla...

Angiotensin converting enzyme (ACE; OMIM: 106180) has an important role in the conversion of angiotensin I to angiotensin II and degradation of bradykinin. Genetic polymorphism I/D (rs4646994) in the gene encoding ACE has been well defined. To get more insight into the genetic structure of Iranian populations, the distribution of the ACE I/D polymorphism among Iranians was compared with each ot...

Although population genetics studies have significantly accelerated the evolutionary and functional interrogations of genes and regulations, limited polymorphism data are available for rhesus macaque, the model animal closely related to human. Here, we report the first genome-wide effort to identify and visualize the population genetics profile in rhesus macaque. On the basis of the whole-genom...

the raini cashmere goat is one of the iranian goat breeds with a high economic value on international markets due to its high production and high quality. the bmp15 gene regulates granulose cell proliferation and differentiation by promoting granulosa cell mitosis, suppressing follicle-stimulating hormone receptor expression, and stimulating the kit ligand expression. this gene plays a pivotal ...