Background and Aims: Inhibition of viral growth in coinfected cells with two different viruses has been described. This phenomenon known as viral interference can occur in several virus host systems such as interference of enterovirus infection on poliovirus vaccine strains. In this study we superinfected reovirus infected HeLa cells with poliovirus to determine if poliovirus can replicate in s...

background and aims: inhibition of viral growth in coinfected cells with two different viruses has been described. this phenomenon known as viral interference can occur in several virus host systems such as interference of enterovirus infection on poliovirus vaccine strains. in this study we superinfected reovirus infected hela cells with poliovirus to determine if poliovirus can replicate in s...

Poliomyelitis (polio) is a highly infectious viral disease, which mainly affects young children. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. Initial symptoms of polio include ...

Given the actual risk of poliomyelitis outbreaks in region due to poliovirus derived from Sabin vaccine or importation wild poliovirus, Latin American Society Pediatric Infectious Diseases commissioned an ad hoc group experts institution's Vaccines and Biologicals Committee, draft official position paper on urgent need increase immunization levels against disease incorporate inactivated polio e...

poliomyelitis (polio) is a highly infectious viral disease, which mainly affects young children. the virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. initial symptoms of polio include ...

objective: as we are approaching the global eradication of wild poliovirus, laboratory surveillance of poliovirus by the gold standard cell culture method becomes increasingly important. as there is a lot of concern about accurate and sensitive detection of imported wild and vaccine derived polioviruses (vdpvs) in polio-free countries, in this study we assessed and compared the sensitivity of t...

BACKGROUND Sensitive poliovirus surveillance to detect vaccine-derived-polioviruses will continue to increase in importance. OBJECTIVE Isolating and identifying poliovirus strains from children of pediatrics age in Nigeria. METHODS A total of 120 fecal samples were randomly collected from children under the age of five who presented with acute flaccid paralysis. Samples were tested by tissu...

Laboratory diagnosis of poliomyelitis is an important part of the WHO initiative for global eradication of poliomyelitis. During the last year, new methods have been developed for the detection of poliovirus in clinical specimens, for intratypic differentiation, for the analysis of poliovirus neurovirulence, and for the detection of poliovirus antibodies. Progress in laboratory techniques for d...

The absolute laboratory containment of any virus cannot be guaranteed, but a wealth of experience indicates that effective containment of wild poliovirus materials for global certification is technically and operationally feasible. Effective containment is based on the principles of minimal wild poliovirus infectious and potentially infectious materials in laboratories; minimal risks of operati...

BACKGROUND Epidemiological studies have indicated that at least 10% of the Dutch elderly do not have poliovirus serotype-specific neutralizing antibody titers and might be at risk for poliovirus infection. Previously we established that memory immunity does not protect the elderly against poliovirus replication. In this study, we investigated whether preexisting immunoglobulin (Ig) A protects a...