background escherichia coli (e. coli) species are able to produce extended-spectrum β-lactamases (esbls) that cause high resistance to the beta-lactam antibiotics. therefore, determining the antibiotic susceptibility patterns in resistant organisms is necessary for suitable therapeutic approaches. patients and methods totally, 260 clinical isolates of e. coli were collected from hospitals in te...

conclusions this study was the first report of the emergence of the plasmid-encoded blaoxa genes among e. cloacae isolates in iran. these findings highlight the need to use appropriate infection control policy and rational antibiotic therapy to reduce further spread of these resistant bacteria in the studied hospitals. results in total, 48 esbl-producing isolates (58.5%) were positive for the b...

background and objectives: the emergence of extended-spectrum β-lactamase (esbl)-producing shigella spp.  is of increasing clinical concern specially in children worldwide. the aim of this study was to investigate the occurrence of extended-spectrum β-lactamase producing shigella spp. in tehran, iran. materials and methods: the study included all shigella isolates recovered from pediatric patie...

background: ampc type β-lactamases are commonly isolated from extended-spectrum cephalosporin-resistant gram-negative bacteria. also, resistance appeared in bacterial species not naturally producing ampc enzymes. therefore, a standard test for the detection of the plasmid-mediated ampc enzyme and new breakpoints for extended spectrum cephalosporins are urgently necessary. objectives: to detect ...

background :   ampc beta lactamases play a significant role in creating resistance to third generation cephalosporins worldwide. they mostly express on chromosome of enterobacteriaceae especially escherichia coli and cause consequential problem in clinical treatment and lead to failure in diagnosis and phenotypic test recommended by clinical and laboratory standards institute.   methods : total...

background and objectives: klebsiella pneumoniae is an opportunistic pathogen responsible for up to 10% of nosocomial infections. the emergence and spread of multidrug resistant k. pneumoniae , mostly due to the production of extended-spec- trum β-lactamases (esbl) and carbapenemases, is often responsible for antibiotic treatment failure of these infections. we compared the antibiotic resistanc...

background and objective: nowadays, the presence of extended-spectrum β-lactamases (esbls) producing strains in serratia genus causes the emergence of resistance to many antibiotics. so, the lack of proper diagnosis of esbls strains can lead to failure in the treatment. the objective of the present study was to investigate esbls production in serratia strains isolated from the clinical blood sa...

background: ampc and esbls as mediated-plasmid extended spectrum β-lactabases are the main factors of resistance to extended-spectrum cephalosporins in enterobacteriacea especially e. coli and will follow treatment failure, high costs of treatment in human and economic losses in the poultry industry. objectives: the purpose of this study was to screen and study the faecal e. coli isolates produ...

extended-spectrum β-lactamase (esbl)-producing enterobacteria has become a considerable global concern because of their potential dissemination in humans, in domestic animals, wildlife and the environment. the present study aimed to explore the esbl producing  enterobacteria in aquatic sources of bangladesh as the water may be the potential source of dissemination of this alarming antimicrobial...

results fifty isolates were positive on the screening test. among them, positive pcr reactions were identified in 35/221 and 12/77 isolates of e. coli and klebsiella spp., respectively, including 16 (34.0%) for cit only, 7 (14.8%) for dha only, and 24 (51.0%) for both dha and cit. no isolate was positive for fox or mox. no proteus organism was positive for ampc genes. conclusions currently, phe...