the ability to taste phenylthiocarbamide (ptc), a bitter organic compound, described as a bimodal autosomal trait is widely used to know the heritable trait in both genetic and anthropological studies. the present study was carried out to analyze the prevalence of ptc taste sensitivity and to determine the gene frequencies among some muslim populations of uttar pradesh, india. this study has so...

This paper introduces a lab project developed for the Summer Teachers’ Workshop in Genomics at Amherst College, and is easily tailored to the weekly format of undergraduate laboratory courses in genetics, genomics, molecular biology, or evolution. The project examines single nucleotide polymorphisms associated with human taste sensitivity to the bitter compound phenylthiocarbamide (PTC). Human ...

The taste of sensitivity Phenylthiocarbamide (PTC), is autosomal dominant trait inherited. taster controled by allele while the non-taster determinated recessive allele. purpose this study was to determine prevalence and frequency alleles for PTC, as well inheritance patterns at population Gili Ketapang island, Probolinggo district. Determination sample or respondents carried out randomly, tota...

The ability to taste phenylthiocarbamide (PTC), is autosomal trait inherited in a simple Mendelian recessive pattern. frequency of Taster and non-Taster allele varies different populations. purpose the research investigate prevalence, gene genotype taster (T) non (ts Osing population Kemiren-Banyuwangi. PTC serial dilution method was used assess phenotypes. Hardy–Weinberg determine frequencies....

OBJECTIVE The aim of this study was to compare taste detection and recognition thresholds of young males and females, and young phenylthiocarbamide (PTC) "tasters" and "nontasters" for stimuli representing sweet, sour, bitter, salty, and umami classes of taste sensations. STUDY DESIGN Thirty-eight men and 37 women (mean [SD] age = 24.5 [2.5] years) were classified as PTC tasters and nontaster...

OBJECTIVE The inability to taste phenylthiocarbamide (PTC) has been associated with medical and neurological illnesses not typically related to taste. The authors examined PTC sensitivity in schizophrenia patients and their non-ill relatives to determine whether this represented a vulnerability marker. METHOD PTC sensitivity was assessed in 42 schizophrenia patients, 23 healthy comparison sub...

BACKGROUND The ability to taste Phenylthiocarbamide (PTC), a bitter organic compound, described as a bimodal autosomal trait is widely used to know the heritable trait in both genetic and anthropological studies. The present study was carried out to analyze the prevalence of PTC taste sensitivity and to determine the gene frequencies among some Muslim populations of Uttar Pradesh, India. This s...

Blood groups (ABO, Rh-including sub-types M-N, Duffy), secretor status and ability to taste Phenylthiocarbamide (PTC) were investigated in 102 medical students of Delhi University, and the distribution was found similar to that observed in the north Indians. Both faster and secretors had highest percentage in AB, O and in rr, while the lowest values were obtained in B and R1r.

Previous work has demonstrated that SWR/J (SW) mice avoid phenylthiocarbamide (PTC) to a greater degree than C3HeB/FeJ mice in 48 h, two-bottle preference tests given in ascending series. The authors hypothesized, based also on previous work, that SW mice might form a conditioned taste aversion over time due to the toxic properties of PTC. We directly tested this hypothesis by attempting to con...

Vegetable consumption by young children does not meet national recommendations in either the United States or in Europe due in part to the bitter taste of vegetables. Cruciferous vegetables contain natural bitter-tasting substances that share the same chemical structure as phenylthiocarbamide (PTC) and its chemical derivative 6-n-propylthiouracil (PROP). The degree to which the bitter taste fro...