Nitin Telang, Ph.D (Reviewer 1): Overall, the manuscript is reasonably well written and contains good data on anti-proliferative and pro-apoptotic effects of Quercetin on Y79 retinoblastoma cell line. The study outcome provides convincing evidence for the involvement of the JNK and p38MAPK pathways in growth inhibitory efficacy. However, the following points need to be considered and appropriat...

formation of non bonded organic layer around inorganic particles like iron sulfide and zeolites, was hypothesized as starting point for one of the possible mechanisms of the origin of life on earth. in this study, the general circumstances needed for creation of such organic layer was investigated. an aliphatic hydrocarbon (hexane), an aromatic hydrocarbon (toluene), an alcohol (n-octanol) and ...

In this article a novel, sensitive and selective cathodic adsorptive stripping procedure is reported for determining of lead. The method is based on adsorptive accumulation of PbN-Nitrozo-N-Phenylhydroxylamine on a hanging mercury drop electrode, followed by the reduction of adsorbed specie by voltammetric scan while followed differential pulse modulation. The optimum conditions for analysis of...

∗ Dr. Jiandong LI is currently a visiting professor at Cornell University from Xidian University, China. He is supported by the Distinguished Visiting Scholar Program of the Chinese Government and TRAPOYT , 863 Project(2001AA123031) and NSFC Project(69872028). ♣ Dr. Zygmunt J. Haas is a professor at Cornell University, USA. His work on this project was supported by the AFOSR and the ONR, as par...

In warm irrigated regions of Australia (such as Sunraysia), pH of grape juice often tends to be high (e.g. > 3.8). A high juice pH is undesirable for the production of quality wines as it results in wines of low quality for example, reduced colour stability and poor taste. Such a high juice pH is typically associated with a high concentration of K in the juice, depending on the scion, rootstock...

For the miniaturization of ISFET sensing systems, the concept of a REFET with low ion sensitivity is proposed to replace the conventional reference electrodes through the arrangement of a quasi reference electrode and a differential readout circuit. In this study, an ion-unblocking membrane was used as the top layer of a REFET. To optimize the REFET performance, the influences of the silylating...

This paper reviews the effect of nutrition on rate of post–mortem pH decline, pH change after electrical stimulation (delta pH) and ultimate pH in skeletal muscle of sheep and cattle. The importance of muscle glycogen concentration as a determinant of ultimate pH, delta pH and rate of pH decline post–mortem is illustrated. As delta pH and rate of pH decline are increased by high muscle glycogen...