An investigation was carried out on snake gourd at the research farm of Department Horticulture, Bangabandhu Sheikh Mujibur Rahman Agricultural University (BSMRAU), Bangladesh during March to June 2019. Significant heterosis observed for most characters studied find high heterotic combination better hybrids. Both positive and negative were found different F1 hybrids over parents. The best paren...

GB virus B (GBV-B), which infects tamarins, is the virus most closely related to hepatitis C virus (HCV). HCV has a protein (p7) that is believed to form an ion channel. It is critical for viability. In vitro studies suggest that GBV-B has an analogous but larger protein (p13). We found that substitutions of the -1 and/or -3 residues of the putative cleavage sites (amino acid 613/614 and 732/73...

ABT-378, a new human immunodeficiency virus type 1 (HIV-1) protease inhibitor which is significantly more active than ritonavir in cell culture, is currently under investigation for the treatment of AIDS. Development of viral resistance to ABT-378 in vitro was studied by serial passage of HIV-1 (pNL4-3) in MT-4 cells. Selection of viral variants with increasing concentrations of ABT-378 reveale...

BACKGROUND Polymorphisms at cleavage sites (CS) can influence Gag and Pol proteins processing by the viral protease (PR), restore viral fitness and influence the virological outcome of specific antiretroviral drugs. However, data of HIV-1 variant-associated CS variability is scarce. METHODS In this descriptive research, we examine the effect of HIV-1 variants on CS conservation using all 9,02...

This study was conducted during the period from 2015 to 2017 resistance of powdery mildew in eight melon inbred lines and their hybrids order reduce losses quality yield.  Eight different genetically were selfed for six generations ensure homozygosity. They have been self-pollinated intercrossed a half diallel mating design obtain 28 2015. Thirty genotypes (8 Lines produced hybrids) evaluated r...

The immunoreactivity of seven peptides synthesized from Schistosoma mansoni proteins, was evaluated by dot-blot and ELISA assays using two different sensitization methodologies. The best results were obtained on wells of the Costar 3590 microplates coated with peptides P1, P2, P3, P6, and P7 using conventional methodology. The signals increased considerably (p < 0.0003) on wells sensitized with...