Two Gram-stain-positive, non-endospore-forming actinobacteria (Ca8(T)and Ca14) were isolated from a bioreactor with extensive phosphorus removal. Based on 16S rRNA gene sequence similarity comparisons, strains Ca8(T) and Ca14 were shown to belong to the genus Gordonia and were most closely related to Gordonia hirsuta DSM 44140(T) (98.0 % sequence similarity) and Gordonia hydrophobica DSM 44015(...

Congenital ataxia and mental retardation are mainly caused by variations in the genes that affect brain development. Recent reports have shown that mutations in the CA8 gene are associated with mental retardation and ataxia in humans and ataxia in mice. The gene product, carbonic anhydrase-related protein VIII (CARP VIII), is predominantly present in cerebellar Purkinje cells, where it interact...

The reliability of an in vitro pyrogen test system based on proinflammatory cytokine release from human monocytic cells was assessed by comparison with a test system based on a human whole blood culture as well as with the conventional rabbit pyrogen test. The human cells used as the pyrogen indicator cells were newly selected by subcloning of a human monocytic cell line, Mono-Mac-6. The select...

We describe a consanguineous Iraqi family in which affected siblings had mild mental retardation and congenital ataxia characterized by quadrupedal gait. Genome-wide linkage analysis identified a 5.8 Mb interval on chromosome 8q with shared homozygosity among the affected persons. Sequencing of genes contained in the interval revealed a homozygous mutation, S100P, in carbonic anhydrase related ...

to evaluate the relationships between soil inorganic phosphorus p (pi) fractions, the soil p test and plant parameters such as plant p uptake, dry matter yield, tissue p concentra-tion and relative yield, glasshouse experiments and chemical analyses were conducted on 13 calcareous soils from six agricultural and seven adjacent bushland (virgin soil) sites. four rates of p (0, 15, 30, 60 mg/kg s...

A unique core-inversible micelle (CIM) was formed via PEG(5k)CA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.

A better understanding of the P dynamic resupply roles fertilization from soil solids to solution is urgently required optimize sustainable fertilizer management practices for efficient supply. five–year experiment was used investigate effects on fractions and availability, kinetic based a novel simulation technique (Diffusive gradients in thin films (DGT) DGT–induced fluxes sediments soils (DI...