terized by ectodermal dysplasia (ED). The nectin-1 (N1) null mutant mice have a mild defect in skin, (Wakamatsu etal., 2007), but no severe phenotypes were reported, suggesting the compensation by other nectins. In this study, we tested this hypothesis by generating N1 and N3 compound mutant mice. We observed coexpression of N1 and N3 in the inner root sheath of hair follicles and in the suprab...
