signal regulatory proteins (sirp) belong to immunoglobulin super family (igsf) and relate to integrin signaling cascades. it has been shown that sirpa is expressed in a variety of cells including myeloid cells and neurons. in the present study the expression of this igsf member in articular chondrocytes was investigated. methods: using a panel of anti-sirpalpha antibodies, immunohistochemistry,...

Background. Patellofemoral osteoarthritis (PF OA) is a leading cause of significant pain and disability of the knee joint. Stair climbing dysfunction is commonly reported in this cohort. Objectives. To compare the temporal muscle activation between females with PF OA and healthy controls during stair ascent and decide whether there is a link between altered core activity and Patellofemoral oste...

objective(s): osteoarthritis (oa) or degenerative joint disease is the commonest form of arthritis and can lead to joint pain, decrease in joint’s range of motion, loss of function, and ultimately disability. exercise is considered as one of the non-pharmacological treatments of oa. but the effects of exercise on knee joint cartilage remain ambiguous. the aim of the present study was to investi...

background osteoarthritis (oa) is a multifactorial, disabling and degenerative disease that worsens with age and affects patient’s health-related quality of life (hrqol). objectives the current study aimed to assess if age and comorbidities have an influence on knee oa and knee replacement outcome before and after the surgery. methods a quasi-experimental intervention study was conducted on a s...

  Objective(s): Osteoarthritis (OA) or degenerative joint disease is the commonest form of arthritis and can lead to joint pain, decrease in joint’s range of motion, loss of function, and ultimately disability. Exercise is considered as one of the non-pharmacological treatments of OA. But the effects of exercise on knee joint cartilage remain ambiguous. The aim of the present study was to inves...

Background: The sternoclavicular joint (SCJ) is the only synovial articulation between the upper extremity and the trunk. This joint is one of the most frequently used joints, so osteoarthritis (OA) should be very common. However, there are few studies about OA in this joint. Methods: In this study, 48 sternoclavicular joints from the left and right joints of 23 cases and two left joints from t...

Background: Intra-articular injection of Platelet-rich plasma (PRP) is an effective method for the treatment of patientswith knee osteoarthritis (OA). This study aimed to assess the effects of PRP injection on OA, based on gene expressionanalysis.Methods: A sample of 30 subjects with knee OA was asked to complete the Persian versions of the Intermittent andConstant Osteo...

background: the sternoclavicular joint (scj) is the only synovial articulation between the upper extremity and the trunk. this joint is one of the most frequently used joints, so osteoarthritis (oa) should be very common. however, there are few studies about oa in this joint.   methods: in this study, 48 sternoclavicular joints from the left and right joints of 23 cases and two left joints from...

conclusions taken together, pomegranate juice did not affect serum cytokines levels in patients with oa. its role in improving physical function in these patients most likely involves other mechanisms. background osteoarthritis (oa) is the most common musculoskeletal disorder causing disability and loss of function, particularly in the elderly. preclinical and in-vitro studies for mitigation of...