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Recombinant Cpn 0810 stimulates proinflammatory cytokine expression and apoptosis in human monocytes
The aim of the present study was to express the recombinant Chlamydophila pneumoniae (C. pneumoniae) protein, Cpn 0810, in Escherichia coli (E. coli) BL21, and investigate the effects of Cpn 0810 on inflammatory and apoptotic processes in human monocytic (THP-1) cells. An ELISA was performed to detect the levels of the proinflammatory cytokines, tumor necrosis factor (TNF)-α and interleukin (IL...
ER-targeted therapeutics provide valuable treatment options for patients with ER+ breast cancer, however, current relapse and mortality rates emphasize the need for improved therapeutic strategies. The recent discovery of prevalent ESR1 mutations in relapsed tumors underscores a sustained reliance of advanced tumors on ERα signaling, and provides a strong rationale for continued targeting of ER...
Naoki Miyagawa1,2 Hiroshi Teramoto1,3 Chun-Biu Li1,2,4 Tamiki Komatsuzaki1,3,4 1Research Institute for Electronic Science Hokkaido University, Sapporo 001-0020, Japan 2Department of Mathematics Hokkaido University, Sapporo 060-0810, Japan 3Graduate School of Life Science Hokkaido University, Sapporo 060-0810, Japan 4Research Center for Integrative Mathematics Hokkaido University, Sapporo 060-08...
Department of Pharmaceutical Science, The Tokushima 770-8505, Japan. E-mail: namba Graduate School of Chemical Sciences Sapporo 060-0810, Japan Department of Chemistry, Faculty of Scienc 060-0810, Japan Catalysis Research Center, Hokkaido Unive † Electronic supplementary information ( for the synthesis of the triazapentalenes absorption and uorescence spectra, an given are the molecular orbita...
1Division of Earth and Planetary Sciences, Graduate School of Science, Hokkaido University, Sapporo, Hokkaido 060-0810, Japan Research Fellow of the Japan Society for the Promotion of Science, Japan 3Division of Natural History Sciences, Graduate School of Science, Hokkaido University, Sapporo, Hokkaido 060-0810, Japan Polar Science Center, Applied Physics Laboratory, University of Washington, ...
Environmental Science Research Laboratory, Central Research Institute of Electric Power Industry, 1646 Abiko, Abiko, Chiba 270-1194, Japan Faculty of Environmental Earth Science, Hokkaido University and CREST-JST, North 10 West 5, Kita-ku, Sapporo, Hokkaido 060-0810, Japan Graduate School of Environmental Science, Hokkaido University, North 10 West 5, Kita-ku, Sapporo, Hokkaido 060-0810, Japan ...
The amounts, sources and relative ages of inorganic and organic carbon pools were assessed in eight headwater streams draining watersheds dominated by either forest, pasture, cropland or urban development in the lower Chesapeake Bay region (Virginia, USA). Streams were sampled at baseflow conditions six different times over 1 year. The sources and ages of the carbon pools were characterized by ...
Tuberculosis (TB) diagnostics are centralised, requiring long-distance transportation of specimens in most resource-limited settings. We evaluated the ability of OMNIgene.SPUTUM (OM-S) to obviate cold-chain transport of TB specimens. A two-arm (same-day and after 5 days sample processing) study was conducted to assess contamination rates and Mycobacterium tuberculosis viability in OM-S-treated ...
MICHAEL P. HAMMER, MARK ADAMS & RALPH FOSTER 1 Natural Sciences, Museum and Art Gallery of the Northern Territory, PO Box 4646 Darwin NT 0810, Australia. E-mail: [email protected] Evolutionary Biology Unit, South Australian Museum, Adelaide SA 5000, Australia. E-mail: [email protected] Ichthyology Section, South Australian Museum, Adelaide SA 5000, Australia. E-mail: ralph.fo...
Department of Microbiology, Faculty of Science, Chulalongkorn University, 254 Phayathai Road, Bangkok 10300, Thailand Bioresources Technology Unit, National Center for Genetic Engineering and Biotechnology (BIOTEC), Pathumthani 12120, Thailand Environmental Molecular Biology Laboratory, Environmental Biology Section, Faculty of Environmental Earth Science, Hokkaido University, N-10 W-5, Sapporo...
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