background ochratoxin a (ota) is a toxic secondary metabolite produced by fungi belonging to aspergillus and penicillium genera. the production of ota is influenced by environmental conditions and nutritional requirements. the postharvest application of bunches of table grape fruit (tgf), with water activity of 0.8 aw, was highly effective for controlling ota contamination in vitro and in vivo ...

the objective of this study was to assess the microbial contamination of razavi khorasan (iran) hot red pepper. the natural occurrence of aflatoxins and ochratoxin a in those samples was also investigated. for this purpose, 36 samples of this kind of pepper were collected from a farm and sun-dried. standard and established methods were used for both microbiological analyses and mycotoxins ident...

mycotoxins are small, toxic chemical products produced as secondary metabolites by a few fungal spices that readily colonise crops and contaminate them with toxins in the field or after harvest. in this study a liquid chromatographic method was developed for the simultaneous determination of aflatoxins (afs) (b 1 , b 2 , g 1 , and g2), ochratoxin a (ota) and zearalenone(zea) toxins in wheat. fo...

Background and Purpose: Breastfeeding plays an important role in the growth and development of infants. However, breast milk may be contaminated with various mycotoxins. Ochratoxin A is one of the most important mycotoxins with nephrotoxic, carcinogenic, teratogenic, genotoxic, and immunotoxic properties. Thus, we carried out this study to determine the concentration of ochratoxin A in human br...

This study finds that the mean IRR for 1980-84 U.S. new drug introductions is 11.1%, and the mean NPV is 22 million (1990 dollars). The distribution of returns is highly skewed. The results are robust to plausible changes in the baseline assumptions. Our work is also compared with a 1993 study by the OTA. Despite some important differences in assumptions, both studies imply that returns for the...

the contamination of cereals with toxic secondary metabolites of fungi, mycotoxins, is a permanent challenge in human health. these toxins are produced by a few fungi are mainly of the genera fusarium , aspergillus and penicillium . ochratoxin a is a nephrotoxic mycotoxin, which possesses carcinogenic, teratogenic, immunotoxic and possibly neurotoxic properties. zearalenone is a non-steroidal e...

background ochratoxins belong to a group of mycotoxins produced as the secondary metabolites by filamentous fungi, such as aspergillus and penicillium. these toxins may be teratogenic, mutagenic, hepatotoxic, nephrotoxic, and may have immunosuppressive effects and pose a serious health problems to exposed humans and animals. objectives the present study aimed to determine the level of ochratoxi...

abstract       background and objective: ochratoxin is a fungal toxin produced by penicillium verrucosum and some aspergillus species. ochratoxin is usually found in grains, cereal products and also animal feed of livestock. the aim of this study was to measure the level of ochratoxin in pasteurized milk samples of golestan province, iran.       methods: overall, 38 milk samples were collected ...

(1)Institute of Human Nutrition and Food Science, Christian-Albrechts-University Kiel (2)Institute of Animal Nutrition and Physiology, Christian-Albrechts-University Kiel Ochratoxin A-induced cytotoxicity in liver (HepG2) cells: Impact of serum concentration, dietary antioxidants and glutathione-modulating compounds* Christine Bösch-Saadatmandi(1), Christoph Hundhausen(1), Laia Jofre-Monseny(1)...