introduction: glaucoma is one of the leading causes of blindness throughout the world. some studies have suggested a relationship between glaucoma and sensorineural hearing loss, while others have found no evidence of an association. we performed a study to determine whether there is a significant difference in hearing of patients with glaucoma and a match control population. methods: in this c...

PURPOSE To determine levels of Peptidyl arginine deiminase 2 (PAD2) and its product protein-bound citrulline in cadaver eyes that suffered from normal tension glaucoma (NTG) compared to primary open angle glaucoma (POAG), and controls. METHODS Western analysis, ELISA, and immunohistochemical analysis were performed with human tissues. RESULTS We report over expression of PAD2 and higher lev...

CEREBROSPINAL FLUID PRESSURE Evidence supports the association of low cerebrospinal fluid (CSF) pressure with the prevalence of glaucoma, particularly with respect to normal-tension glaucoma (NTG). The most robust study comes from Tongren Hospital in Beijing, China, in which patients with both high-tension and normal-tension open-angle glaucoma as well as healthy controls underwent lumbar punct...

• Vol 7 • October 2005 Normal-Tension Glaucoma Open-angle glaucoma with normal intraocular pressure, also known as normal-tension glaucoma, is estimated to constitute 10–25% of all glaucoma cases. NTG is a diagnostic challenge, as various lesions affecting the visual pathways including compression by normal or abnormal intracranial blood vessels can mimic its clinical findings. In recent years,...

PURPOSE The aim of this study was to compare the ocular pulse amplitude (OPA) in patients with different types of glaucoma, and also to evaluate the usefulness of OPA for the elucidation of normal-tension glaucoma (NTG). OPA is thought to reflect choroidal circulation. SUBJECTS Sixty-six patients with normal-tension glaucoma (NTG), 52 patients with primary open angle glaucoma (POAG), 42 with ...

The diagnosis and treatment of normal tension glaucoma remain controversial. The diagnostic dilemma is further compounded by the vast array of investigative modalities available. Also the concept of target IOP and physical quality of life of the patient is an important determinant of current glaucoma practice.This review provides a logical algorithm for the diagnosis, investigation and manageme...

Normal tension glaucoma (NTG) remains a diYcult diagnosis for the ophthalmologist who favours the argument that raised intraocular pressure (IOP) is essential for the diagnosis of primary open angle glaucoma (POAG). The concept of NTG challenges us to distinguish between pressure dependent and pressure independent causal factors. The purpose of this review is to present some of the current info...

Glaucoma is a primary cause of irreversible blindness worldwide, it kills the vision silently, having financial burden on society regarding therapy expenses and loss valuable hours day. Objective: To compare choroidal filling time grade status pattern optic nerve head (ONH) perfusion by fundus fluorescein angiography (FFA) in glaucoma patients Methods: Patients with various types were enrolled ...