Several rabies virus (RV) vaccine strains containing an aspartic acid (Asp) or glutamic acid (Glu) instead of an arginine (Arg) at position 333 of the RV glycoprotein (G) are apathogenic for immunocompetent mice even after intracranial inoculation. However, we previously showed that the nonpathogenic phenotype of the highly attenuated RV strain SPBNGA, which contains a Glu at position 333 of G,...

We performed electron spin resonance (ESR) measurements on two kinds of nickel chain compounds doped with nonmagnetic Zn2+ ions, Ni(333-tet)( -NO2)(ClO4) (333-tet=bis-(3-aminopropyl)-1,3-propanediamine) abbreviated as NTENP and Ni(1,3-pn)2( -NO2)(ClO4) (1,3-pn=1,3-propanediamine) abbreviated as NINO which are regarded as a spin (S) one Heisenberg antiferromagnetic bond alternating chain and a u...

Susceptibility, ESR, and magnetization measurements have been performed on single crystals of an S = 1 bond alternating chain compound: [Ni(333-tet) (mu-NO2)] (ClO4) (333-tet = N,N'-bis(3-aminopropyl)propane-1,3-diamine) and the compound doped with a small amount of Zn. We observed an anomalous angular dependence in the Zn-doped sample. These results are well explained by the model based on the...

Under 5 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114 4.6 5 to 9 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154 6.3 10 to 14 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 145 5.9 15 to 19 years . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 163 6.6 20 to 24 years . . . . . . . . . . . . . . . . . . . . ....

A novel technique has been developed for the detection of peroxy radicals in order to study their kinetics with NO2. Peroxy radicals (RO2, where R = H, CH3, and 1,2-C4H9) were produced by laser flash photolysis and were probed by photodissociation of the RO2 and the subsequent detection of either OH or CH3O photofragments by laser-induced fluorescence. Reaction 1 , CH3O2 + NO2 + M ⇌ CH3O2NO2 + ...

1Elements Strategy Initiative Center for Magnetic Materials, National Institute for Materials Science, Tsukuba 305-0047, Japan 2Computational Materials Science Center, National Institute for Materials Science, Tsukuba 305-0047, Japan 3Research Center for Strategic Materials, National Institute for Materials Science, Tsukuba 305-0047, Japan 4School of Physics, University of Sydney, Sydney 2006, ...

Type 2 diabetes mellitus already a substantial public health problem in most industrialized nations, is increasing in prevalence worldwide. According to the International Diabetes Federation, the global prevalence of diabetes is expected to increase from 194 million cases in 2003 to an estimated 333 million cases in 2025. Particularly hard hit will be developing countries, where type 2 diabetes...

The Multicenter Lifestyle Demonstration Project was designed to determine if comprehensive lifestyle changes can be a direct alternative to revascularization for selected patients without increasing cardiac events. A total of 333 patients completed this demonstration project (194 in the experimental group and 139 in the control group). We found that experimental group patients were able to avoi...

The pathogenicity of fixed rabies virus strains for adult mice depends on the presence of an antigenic determinant on the viral glycoprotein. Two virus-neutralizing monoclonal antibodies have been used to identify this determinant. All pathogenic strains of fixed rabies virus bind to these antibodies and are neutralized by them, whereas nonpathogenic strains fail to react with these monoclonal ...

A novel blue-emitting Sr3.5Y6.5O2(PO4)1.5SiO4(4.5) :Eu2+ phosphor was synthesized via a solid-state reaction. Powder X-ray diffraction (XRD) analysis demonstrated that the Sr3.5Y6.5O2(PO4)1.5(SiO4)4.5 host had a hexagonal crystal structure in the space group P6(3) /m and unit cell parameters a = 9.418 Å, c = 6.900 Å. The as-prepared phosphor showed a blue emission and all the main emission peak...