The purpose of this study was the surface modification of nano MOF-5 (NMOF-5) or IRMOF-1 (Zn4O(C8H4O4)3) in order to prevent its rapid degradation in the phosphate-buffered saline (PBS), along with the simultaneous increase in its biocompatibility. The NMOF-5 sample was synthesized under the ultrasound irradiation and then it was loaded wit...

Lithium polysulphides generated during discharge in the cathode of a lithium-sulphur redox cell are important, but their dissolution into the electrolyte from the cathode during each redox cycle leads to a shortened cycle life. Herein, we use in situ spectroelectrochemical measurements to demonstrate that sp(2) nitrogen atoms in the organic linkers of nanocrystalline metal-organic framework-867...

The growth of nanocrystalline metal-organic frameworks (nMOFs) around metal nanocrystals (NCs) is useful in controlling the chemistry and metric of metal NCs. In this Letter, we show rare examples of nMOFs grown in monocrystalline form around metal NCs. Specifically, Pt NCs were subjected to reactions yielding Zr(IV) nMOFs [Zr6O4(OH)4(fumarate)6, MOF-801; Zr6O4(OH)4(BDC)6 (BDC = 1,4-benzenedica...

Bio-inspired self-cleaning surfaces have found industrial applications in oil–water separation, stain resistant textiles, anti-biofouling paints in ships etc. Interestingly, self-cleaning metal–organic framework (MOF) materials having high water contact angles and corrosion resistance have not been realized so far. To address this issue, we have used the fundamentals of self-assembly to expose ...

Real-time measurement of intracellular pH in live cells is of great importance for understanding physiological/pathological processes and developing intracellular drug delivery systems. We report here the first use of nanoscale metal-organic frameworks (NMOFs) for intracellular pH sensing in live cells. Fluorescein isothiocyanate (FITC) was covalently conjugated to a UiO NMOF to afford F-UiO NM...

A nanoscale aluminium-based metal organic framework (NMOF) with high thermal stability has been synthesized, which shows high H(2) and CO(2) uptake capacities and an excellent selectivity for CO(2) over N(2) and O(2).

Nitrogen-doped graphitic porous carbons (NGPCs) have been synthesized by using a zeolite-type nanoscale metal-organic framework (NMOF) as a self-sacrificing template, which simultaneously acts as both the carbon and nitrogen sources in a facile carbonization process. The NGPCs not only retain the nanopolyhedral morphology of the parent NMOF, but also possess rich nitrogen, high surface area and...

A versatile approach to modify metal–organic framework nanoparticles (NMOFs) with nucleic acid tethers, using the “click chemistry” method is introduced. The nucleic acid-functionalized NMOFs are used to prepare stimuli-responsive carriers of loads (fluorescence probes or anti-cancer drugs). Two different stimuli-responsive nucleic acid-based NMOFs are presented. One system involves the prepara...

MOTIVATION Although trauma is the leading cause of death for those below 45years of age, there is a dearth of information about the temporal behavior of the underlying biological mechanisms in those who survive the initial trauma only to later suffer from syndromes such as multiple organ failure. Levels of serum cytokines potentially affect the clinical outcomes of trauma; understanding how cyt...

We investigated systematically the effects of Tet-induced oxidation products of 5-methylcytosine on Dnmt1- and DNMT3a-mediated cytosine methylation in synthetic duplex DNA. We found that the replacement of 5-methylcytosine at a CpG site with a 5-hydroxymethylcytosine, 5-formylcytosine, 5-carboxylcytosine or 5-hydroxymethyluracil resulted in altered methylation of cytosine at both the opposite a...