background: delayed graft function is a main complication after deceased donor kidney transplantation that adversely affects graft outcome. difficulties in prediction and early detection of delayed graft function have hindered the ability to perform proper therapeutic interventions. we investigated whether measuring urinary interleukin 18 and neutrophil gelatinase-associated lipocalin as marker...

Background: Delayed graft function is a main complication after deceased donor kidney transplantation that adversely affects graft outcome. Difficulties in prediction and early detection of delayed graft function have hindered the ability to perform proper therapeutic interventions. We investigated whether measuring urinary interleukin 18 and neutrophi...

objective(s) lipocalin 2 (lcn2) is a 25-kda glycoprotein that has initially been extracted from neutrophil granules. expression of lcn2 is induced under various pathophysiological conditions. it is also known as an early marker of kidney and heart injury. high-level expression of recombinant lcn2 neutrophil gelatinase-associated(ngal) in insect cells was the aim of this study. materials and met...

Complex Information for Anesthesiologists Presented Quickly and ClearlyCPB, cardiopulmonary bypass; IGFBP7, insulin-like growth factor binding protein 7; IL-18, interleukin-18; KDIGO, Kidney Disease: Improving Global Outcomes; KIM-1, kidney-injury- molecule-1; NGAL, neutrophil gelatinase-associated lipocalin; TEE, transesophageal echocardiography; TIMP-2, tissue inhibitor of metalloproteinase 2...

background: hypertension is one the most common causes of chronic kidney disease (ckd). one of the major concerns in hypertensive patients is early detection of renal disorders. in the past, serum creatinine (scr) concentration was used as a marker of kidney function, but it proffers a late reflection of reduced glomerular filtration rate. cystatin c and neutrophil gelatinase-associated lipocal...

BACKGROUND Delayed graft function is a main complication after deceased donor kidney transplantation that adversely affects graft outcome. Difficulties in prediction and early detection of delayed graft function have hindered the ability to perform proper therapeutic interventions. We investigated whether measuring urinary interleukin 18 and neutrophil gelatinase-associated lipocalin as markers...

conclusions sepsis enhances the production of plasma ngal in critically ill neonates. thus plasma ngal can help clinicians diagnose sepsis in critically ill neonates during early phases. results the ngal levels were significantly higher in septic neonates compared with non-septic neonates (102.9 ± 69.9 ng/ml versus 29.2 ± 13.3 ng/ml, p value = 0.0001). an optimal cut off-point of 48 ng/ml for s...

OBJECTIVE To assess the diagnostic and prognostic efficacy of urine neutrophil gelatinase-associated lipocalin in patients admitted to an intensive care unit. METHODS Longitudinal, prospective cohort study conducted in a cardiology intensive care unit. The participants were divided into groups with and without acute kidney injury and were followed from admission to the intensive care unit unt...

Neutrophil gelatinase-associated lipocalin is currently one of the most interesting and enigmatic proteins involved in the development of malignancies. In this study, we found that the expression of neutrophil gelatinase-associated lipocalin was up-regulated in endometrial cancer tissues and cell lines, significantly increased in early-grade ones, suggesting it may serve as a biomarker for earl...

background early predictive biomarkers for acute kidney injury (aki) such as neutrophil elatinase-associated lipocalin (ngal) could identify patients who may benefit from early initiation of treatment. objectives we aimed to obtain a cut off point for aki prediction by urine ngal in kidney transplantation. patients and methods in a prospective cohort study, 64 adult who underwent kidney transpl...