1,2-Naphthoquinone-4-Sulphonic Acid Sodium Salt (NQS) as an Analytical Reagent for the Determination of Pharmaceutical Amine by Spectrophotometry Abdalla Ahmed Elbashir a , Abir Abdalla Ahmed a , Shazalia M. Ali Ahmed a & Hassan Y. Aboul-Enein b a University of Khartoum, Faculty of Science, Chemistry Department, Khartoum, Sudan b Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical...

A simple and reliable precolumn derivatization liquid chromatography method with ultraviolet detection has been developed and validated for the analysis of glucosamine (GS) in various dietary supplement formulations and raw materials. Additionally, the proposed method was used for analysis of carisoprodol (CR) found in ternary mixture with paracetamol (PR) and caffeine (CF). The linearity range...

two simple visible spectrophotometric methods are developed and validated for the quantification of modafinil using 1,2-naphthoquinone-4-sulphonic acid (nqs method) and 2,4-dinitrophenol (dnp method) as analytical reagents. the nqs method involves the reaction of modafinil with 1,2-naphthoquinone-4-sulphonate in alkaline medium at room conditions to form a yellow colored product exhibiting maxi...

Two simple visible spectrophotometric methods are developed and validated for the quantification of modafinil using 1,2-naphthoquinone-4-sulphonic acid (NQS method) and 2,4-dinitrophenol (DNP method) as analytical reagents. The NQS method involves the reaction of modafinil with 1,2-naphthoquinone-4-sulphonate in alkaline medium at room conditions to form a yellow colored product exhibiting maxi...

Some reactive dyes (6a-6l) having Quinazolin-4(3H)-one system have been synthesized by coupling of diazotized 3-(4-(5-(4-aminophenyl)-1,3,4-oxadiazol-2-yl) phenyl)-4-oxo-2-phenyl-3,4-dihydroquinazoline-6-sulphonic acid with cyanurated components such as H-acid, J-acid, N-methyl Gamma acid, Peri Sulpho Tobias Koch Bronners Chicago K-acid, N-Phenyl J-acid and M-acid. The were characterized nitrog...

Reaction of 1,2-naphthoquinone with primary amines gives a 2-amino-1,4-naphthoquinone derivative which is equivalent to 1,2 to 1,4 carbonyl transposition. For example the reaction of 1,2-naphthoquinone with 4-methoxyaniline gives 2-(4-methoxyanilino)-naphthoquinone-1,4-(4-methoxyanil) (1) and with n-butylamine gives 2-(butylamino)-naphthoquinone-1,4-butylimine (2) respectively. The compounds 1 ...

1. 2-Naphthylhydroxylamine and 2-nitrosonaphthalene were present in urine of dogs but not of guinea pigs, hamsters, rabbits or rats dosed with 2-naphthylamine. N-Acetyl-2-naphthylhydroxylamine and its O-sulphonic acid and O-glucosiduronic acid were not detected in the urine of any of these species. 2. Bile from rats dosed with 2-naphthylamine contained (2-naphthylamine N-glucosid)uronic acid an...

The effects of p-chloromercuribenzoic acid and chloromercuribenzene-p-sulphonic acid on pancreatic islets were studied in vitro. Obese-hyperglycaemic mice were used as the source of microdissected islets containing more than 90% beta-cells. p-Chloromercuribenzoic acid and chloromercuribenzene-p-sulphonic acid stimulated insulin release at concentrations of 0.01mm or above. This stimulation was ...

incorporation of this acid in vitamin K 2 23 and vitamin K t 4 in bacteria and higher plants. Degradation of labeled vitamin K 2 after feeding shikimic acid (-U-1 4C) has shown that the intact ring of this acid is incorporated into the benzenoid moiety of this naphthoquinone 2 ' 3 . fn contrast, the degradation studies on lawsone 1 indicated that the ring atoms of shikimic acid (-U-1 4C) are tr...