نتایج جستجو برای: nanodrug delivery system
تعداد نتایج: 2388923 فیلتر نتایج به سال:
aim and background: hepatocellular carcinoma (hcc) -an aggressive malignancy with high rate of mortality- is the third cause of cancer related death, worldwide. cisplatin is a chemotherapy drug used for treatment of hcc. however, serious side effects of drug limit the therapeutic administer dose. nanotechnology based devices such as liposome nanoparticles are capable to overcome these drawback...
To date, various nanodrug systems have been developed for different routes of administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles. Nanodrug systems have been employed to improve the efficacy, safety, physicochemical properties, and pharmacokinetic/pharmacodynamic profile of pharmaceutical substances. In p...
The development of multidrug resistance (MDR) has become an increasingly serious problem in cancer therapy. The cell-membrane overexpression of P-glycoprotein (P-gp), which can actively efflux various anticancer drugs from the cell, is a major mechanism of MDR. Nuclear-uptake nanodrug delivery systems, which enable intranuclear release of anticancer drugs, are expected to address this challenge...
The chemical structure of CyssTP and its self-assembly into a glutathione-activated carrier-free nanodrug triptolide (CyssTPN) as trackable drug delivery system for tumor therapy.
The human immunodeficiency virus 1 (HIV-1) still remains one of the leading life-threatening diseases in the world. The introduction of highly active antiretroviral therapy has significantly reduced disease morbidity and mortality. However, most of the drugs have variable penetrance into viral reservoir sites, including gut-associated lymphoid tissue (GALT). Being the largest lymphoid organ, GA...
Nanotechnology is of intense interest to researchers due the basic fact that properties material can be effectively manipulated when size transformed nanoscopic. New opportunities arise out unique features which have been effectually utilized in development nano pharmaceuticals. This has revolutionized health care system extensively by its diverse applications modern medicine and dental science...
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