n-hexane neuropathy has been described after glue sniffing and industrial exposure. onset may be subacute and reminiscent of guillain-barre' syndrome. five patients (15-18 years old) presented with paresthesia, severe weakness of the extremities particularly lower extremities, as well as muscular atrophy, total areflexia and gait disturbances were admitted in hospital in march 2003. all of thes...

In the title compound, C(8)H(12)O(2), the cyclo-hexane ring exhibits a chair conformation and the δ-lactone ring is axially bonded to the cyclo-hexane ring. In the crystal, mol-ecules are linked by C-H⋯O hydrogen bonds, resulting in ribbons extending along [010].

The crystal structure of the title compoud, C(17)H(20)BrNO(3), contains three chiral centers, which all exhibit an S configuration. The C=C double bond has an E conformation. The cyclo-hexane ring is in a chair conformation. In the crystal, mol-ecules are linked by weak N-O⋯Br inter-actions [O⋯Br = 3.136 (4) Å].

In title compound, C(16)H(17)FN(2)O(2), the cyclo-hexane ring adopts a chair conformation.. The crystal packing is stabilized by weak π-π stacking inter-actions [centroid-centroid distance = 3.503 (5) Å] and inter-molecular C-H⋯O, N-H⋯O and N-H⋯F hydrogen-bond inter-actions.

In the title compound, C(8)H(10)N(2), the cyclo-hexane ring adopts a chair conformation. he crystal structure of the previously reported monoclinic modification have intramolecular CN⋯CN and C-H⋯N interactions. These types of interaction are not present in this new modification whose crystal structure is built up by van der Waals interactions.

In the title compound, C(14)H(17)NO(2), the two carbonyl groups are oriented with respect to each other with a torsion angle of -129.9 (3)°. The cyclo-hexane ring adopts a chair conformation. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds into a chain running along the a axis.

In the title compound (5S,8R,9R,10R,13S,14S,17R,20R)-24-bromo-5β-cholane, C(24)H(41)Br, the fused-chair conformation of the cyclo-hexane A/B ring junction is cis with a 5β-H configuration.