نتایج جستجو برای: microdialysis.

تعداد نتایج: 3833  

Journal: :Sensors & diagnostics 2023

A copolymer-modified glass nanopore combined with microdialysis was used for assaying cerebral Aβ monomer and Zn 2+ . In the presence of monomer, copolymer stretched. Then, altered surface charges fluorescence.

Journal: :medical journal of islamic republic of iran 0
h alaei from thedepartment of physiology, university of esfahan, iran, thedepartment of pharmacology and toxicology, university of kuopio, finland m huotari thedepartment of pharmacology and toxicology, university of kuopio, finland pt piepponen the unit of pharmacology and toxicology, department of pharmacy, university of helsinki, helsinki, finland, l ahtee the unit of pharmacology and toxicology, department of pharmacy, university of helsinki, helsinki, finland, o hanninen department of physiology, university of kuopio, finland pt mannisto thedepartment of pharmacology and toxicology, university of kuopio, finland

in vivo microdialysis was used to study the effects of morphine on glutamate release from the ventral tegmentum area (vta) in freely moving rats. intraperitoneal (i.p.) injection of acute and repeated morphine at increasing doses significantly enhanced glutamate release. only a minor tolerance developed to this dosage of morphine. ap-s (2-amino-5-phosphonovaleric acid, 0.5 mg/kg i.p.), a nmda r...

Journal: :Journal of Neuroanaesthesiology and Critical Care 2015

Journal: :Acta neurobiologiae experimentalis 2004
Monika Orłowska-Majdak

In vivo microdialysis allows sampling of brain regions in conscious, freely moving animals. Moreover, the in vivo microdialysis allows to administer drugs directly into specific brain areas. Both are useful in behavioral studies. The subject of this review is the methodology of brain microdialysis, that is construction of the probe, effect of temperature, composition of the perfusion medium, pe...

Journal: :medical journal of islamic republic of iran 0
a vahabzadeh from the department of physiology, iran university of medical sciences, tehran, i.r. iran m fillenz the university laboratory of physiology, university of oxford, oxford, u.k.

microdialysis was used to measure the effect of benzodiazepines (bdzs) on basal levels and on stress-induced increases of 5 -hydroxytryptamine (5 -ht), 5 - hydroxyind oleacetic acid (5 -hiaa) , noradrenaline (na), and dihydroxyphenylacetic acid (dop ac). the stressors used were a 5 min tail pinch or a 10 min period of restraint. a subcutaneous injection of 5 mg/kg diazepam decreased basal level...

Journal: :Acta dermato-venereologica 1998
L Groth A Jørgensen J Serup

Microdialysis is a method by which compounds can be studied in the extracellular space in skin, in vivo. The microdialysis probe is inserted in the dermis using a guide cannula. It is expected that intradermal oedema associated with insertion trauma as well as the probe depth can influence the results of microdialysis studies. The aim of the present study was to assess the effects of insertion ...

Baochang Cai Gang Cao, Hao Cai Jian Feng Xiaodong Cong Yun Zhang

      The purpose of this study was to develop a sensitive and fast microdialysis coupled with high-performance liquid chromatographic (HPLC) method for determination of 5-hydroxymethyl-2-furaldehyde (5-HMF) in free-moving rats after i.g. administration of the aqueous extract of crud Fructus corni and its processed products of jiuzheng pin (JZP). The concentration of 5-HMF in free-movi...

Journal: :Clinical physiology and functional imaging 2011
Pernilla Abrahamsson Anna-Maja Aberg Göran Johansson Ola Winsö Anders Waldenström Michael Haney

Microdialysis (MD) can be used to study metabolism of the beating heart. We investigated whether microdialysis results obtained from epicardial (surface) sampling reflect acute changes in the same way as myocardial sampling from within the substance of the ventricular wall. In anaesthetized open-thorax pigs a coronary snare was placed. One microdialysis probe was placed with the sampling membra...

2012
Yuexiang Wang Adrian C. Michael Steve Weber Megan Spence Michael Zigmond

Extracellular dopamine (DA) is critical in regulating DA release as well as interacting with other neurotransmission systems. Microdialysis and voltammetry are the major techniques for extracellular DA measurement in vivo. These two techniques provide distinct results due to their different detection volumes. Carbon fiber microelectrode is 10,000 times smaller than that of a microdialysis probe...

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