نتایج جستجو برای: miRNA and multiple sclerosis

تعداد نتایج: 16931715  

Background and objectives: One of the latest studies in the genetics field is the evaluation of role of micro-RNAs as a biomarker for diagnosis of multiple sclerosis (MS), which is a demyelinating disease of the central nervous system (CNS) and emerges in the form of numerous small and large plaques in white matter in the brain and spinal cord. This disease could be associated with several comp...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهید باهنر کرمان - دانشکده ادبیات و زبانهای خارجی 1392

abstract the current research tried to examine the impact of multiple intelligence (mi) and its components on multiple choice (mc) and open ended (oe) reading comprehension tests. ninety six students of high school in grade four took part in this study. to collect data, participants completed multiple intelligence (mi) questionnaires along with a multiple choice (mc) and open ended (oe) forms ...

Introdution: Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system. Nevertheless, the causal etiology of MS is not fully revealed and there are some neurological disorders that might have similar phenotypic manifestations with MS. Therefore, reliable and available diagnostic method is very necessary for differential diagnosis. The use of new biomarkers for fas...

Journal: :jentashapir journal of health research 0
shahnaz mohammadi department of psychology, kharazmi university, tehran, ir iran maryam izadi-mazidi department of psychology, department of psychology, shahed university, tehran, ir iran; department of psychology, shahid chamran university, ahvaz, ir iran. tel: +98-9171346040 negin kazemi department of psychology, kharazmi university, tehran, ir iran

conclusions our study suggests that the personality traits of patients with ms and healthy individuals are not significantly different. patients with ms are likely to use the same coping strategies as healthy individuals, except in the subscale of distancing. results no significant differences in personality characteristics were observed between patients and healthy controls (all p > 0.05). onl...

Masoud Amiri, Mohammad Saeid Jami Reza Sahebi

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system (CNS). This highlydisabling disorder is characterized by a variable clinical course. MS is a heterogeneous disease with acomplex pathology and significant social and economic impact. MS is associated with dysfunction ofparts of the nervous system which results in a range of signs and symptoms, ...

Bahram Moghimi, Ehsan Farashahi Yazd, Ensieh Shahvazian, Mohammadbagher Mahmoudi, Mohammadtaher Tahoori, Saba Gharibi,

Multiple sclerosis (MS) is the most common autoimmune inflammatory demyelinating disease that affects the brain and spinal cord. Dysregulation or mutation of miRNA genes have been linked to the pathogenesis of MS. The miRNAs are short, 20-22 nucleotide long, single-stranded regulatory and non-protein coding RNAs that modulate the expression of multiple target genes. Among miRNAs, miR-223 has be...

2009
David Otaegui Sergio E. Baranzini Ruben Armañanzas Borja Calvo Maider Muñoz-Culla Puya Khankhanian Iñaki Inza Jose A. Lozano Tamara Castillo-Triviño Ana Asensio Javier Olaskoaga Adolfo López de Munain

Differences in gene expression patterns have been documented not only in Multiple Sclerosis patients versus healthy controls but also in the relapse of the disease. Recently a new gene expression modulator has been identified: the microRNA or miRNA. The aim of this work is to analyze the possible role of miRNAs in multiple sclerosis, focusing on the relapse stage. We have analyzed the expressio...

پایان نامه :وزارت بهداشت، درمان و آموزش پزشکی - دانشگاه علوم پزشکی و خدمات بهداشتی درمانی استان کرمان 1389

چکیده ندارد.

Journal: :medical journal of islamic republic of iran 0
alireza olyaeemanesh national institute for health research, tehran university of medical sciences, tehran, iran. mahbobeh rahmani health school department of yazd university of medical sciences, iran. reza goudarzi kerman university of medical sciences, kerman, iran. abulghasem rahimdel shahid sadooghi hospital, yazd university of medical science, yazd, iran.

background: intravenous immunoglobulin (ivig) is an established treatment of immune mediated demyelinating neuropathy including guillain-barré syndrome and chronic inflammatory demyelinating polyneuropathy. recent trials suggest its efficacy in treating relapsing- remitting multiple sclerosis. ivig exerts a number of effects, which may be beneficial in treating multiple sclerosis (ms): reductio...

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