Swissmedic und die Europäische Arzneimittelagentur informierten, dass Peri-/Myokarditiden nach Applikation der Messenger-RNA-(mRNA-)COVID-19-Impfstoffe Tozinameran (Pfizer/­BioNtech) mRNA-1273 (Moderna) auftreten können.

Induction of protein synthesis by the external delivery of in-vitro transcription-messenger RNA (IVT-mRNA) has been a useful approach in the realm of cell biology, disease treatment, ‎reprogramming of cells, and vaccine design. Therefore, the development of new formulations for ‎protection of mRNA against nucleases is required to maintain its activity in-vivo. It was the aim o...

Induction of protein synthesis by the external delivery of in-vitro transcription-messenger RNA (IVT-mRNA) has been a useful approach in the realm of cell biology, disease treatment, ‎reprogramming of cells, and vaccine design. Therefore, the development of new formulations for ‎protection of mRNA against nucleases is required to maintain its activity in-vivo. It was the aim o...

Ongoing research into the use of messenger RNA (mRNA) vaccines for treatment cancer has been expediated by coronavirus pandemic because similar technology was used in development mRNA COVID‐19 vaccines. So how close are we now to widespread clinical anti‐cancer vaccines?

Comprehensive identification of potential immune-related genes related to tumor biological behavior and their significance in the treatment head neck squamous cell carcinoma with a messenger RNA (mRNA) vaccine

The COVID-19 pandemic has stimulated the production of different therapeutic approaches for resolution coronavirus infections. On one hand, nanobiomolecules have been proposed as bait material viruses,1,2 on other hand unconventional messenger RNA vaccines produced like SARS-CoV-2 mRNA (BioNTech/Pfizer BNT162b2 and Moderna mRNA-1273). [...]

Genetic regulation of organisms involves complicated RNA–RNA interactions (RRIs) among messenger RNA (mRNA), microRNA (miRNA), and long non-coding (lncRNA). Detecting RRIs is beneficial for discovering biological mechanisms as well designing new drugs. In recent years, with more experimentally verified being deposited into databases, statistical machine learning, especially deep-learning-based ...

The global COVID-19 pandemic has brought tremendous momentum to the field of messenger RNA (mRNA) vaccines. advantages this vaccine platform, such as rapid development and high efficacy, resulted in mRNA vaccines being first approved against COVID-19. Looking forward future vaccines, how can we make even better? While improvements stability formulation cost are inevitable, one main challenges i...

Background: Human consumption of food and herbal medicines supplies the body with not only nutrients but also associated biologically active compounds, such as exogenic messenger RNA (mRNA) inhibitory RNAs (miRNAs). Therefore, it seems important to establish which maize wheat miRNAs can enter human evaluate their possible actions binding features mRNA genes. It is required determine whether mos...