نتایج جستجو برای: mean-QD model

تعداد نتایج: 2588699  

D. A. Ralescu X. Wu Y. Liu,

The aim of this paper is to propose a convex risk measure in the framework of fuzzy random theory and verify its advantage over the conventional variance approach. For this purpose, this paper defines the quadratic deviation (QD) of fuzzy random variable as the mathematical expectation of QDs of fuzzy variables. As a result, the new risk criterion essentially describes the variation of a fuzzy ...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد گرمسار - پژوهشکده علوم انسانی و اجتماعی 1391

abstract the present study was conducted to investigate the effect of using model essays on the development of writing proficiency of iranian pre-intermediate efl learners. to fulfill the purpose of the study, 55 pre- intermediate learners of parsa language institute were chosen by means of administering proficiency test. based on the results of the pretest, two matched groups, one as the expe...

Journal: :Clinical therapeutics 2015
Kristy Iglay Xiting Cao Panagiotis Mavros Kruti Joshi Shengsheng Yu Kaan Tunceli

PURPOSE To compare medication adherence rates for once-weekly (QW) versus once-daily (QD) dosing regimens in patients with chronic disease. METHODS A systematic literature review was conducted to identify articles published in English-language journals examining the rate of adherence to medications in patients with chronic disease. Relevant studies were identified from January 2002 through Au...

2016
William B Saunders Hiep Nguyen Iftekhar Kalsekar

AIM The glucagon-like peptide-1 receptor agonists exenatide once weekly (QW) and liraglutide once daily (QD) have demonstrated improvements in glycemic outcomes in patients with type 2 diabetes mellitus in randomized clinical trials. However, little is known about their real-world comparative effectiveness. This retrospective cohort study used the Quintiles Electronic Medical Record database to...

In this paper, modulation bandwidth characteristics of InGaAs/GaAs quantum dot (QD) laser were theoretically investigated. Simulation was done by using the fourth order Runge-Kutta method. Effect of carrier relaxation life time, temperature and current density on characteristics of tunneling injection QD laser (TIL) and conventional QD laser (CL) were analyzed. Results showed that tunneling inj...

2014
Alison Church Misba Beerahee Jean Brooks Rashmi Mehta Palvi Shah

BACKGROUND Umeclidinium bromide (UMEC) is an inhaled long-acting muscarinic antagonist in development for chronic obstructive pulmonary disease (COPD). METHODS This was a multicentre, randomised, double-blind, placebo-controlled, three-way cross-over, incomplete block study to evaluate UMEC 15.6, 31.25, 62.5, and 125 μg administered once daily (QD), and UMEC 15.6 μg and 31.25 μg administered ...

Journal: :Pediatrics 2003
Stanley P Galant Isaac R Melamed Anjuli S Nayak Kathryn V Blake Barbara A Prillaman Kenneth D Reed Cindy K Cook Edward E Philpot Kathleen A Rickard

OBJECTIVE Fluticasone propionate aqueous nasal spray (FP) at the highest recommended doses does not affect hypothalamic-pituitary-adrenal (HPA) axis function in adults or older children, but its potential effects in children younger than 4 years have not been previously studied. This randomized, double-blind, placebo-controlled study evaluated the effects of FP on HPA axis function measured by ...

2008
Douglas J Rhee James H Peace Sushanta Mallick Theresa A Landry Michael VW Bergamini

BACKGROUND/AIMS To compare the intraocular pressure (IOP)-lowering efficacy of travoprost 0.004%/timolol 0.5% in fixed combination with the unfixed combination of latanoprost 0.005% and timolol 0.5% in open-angle glaucoma or ocular hypertension patients with IOP levels below 18 mmHg on the unfixed combination of latanoprost 0.005% and timolol 0.5%. METHODS Following a 30-day open-label run-in...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2011
Patricia M Lorusso Antonio Jimeno Grace Dy Alex Adjei Jordan Berlin Lawrence Leichman Jennifer A Low Dawn Colburn Ilsung Chang Sravanthi Cheeti Jin Y Jin Richard A Graham

PURPOSE This study was designed to evaluate whether less frequent dosing [three times per week (TIW) or once weekly (QW)] of 150 mg vismodegib following a loading dose [150 mg once daily (QD) for 11 days] would result in similar safety, tolerability, and steady-state levels of total and unbound vismodegib as continuous QD dosing. EXPERIMENTAL DESIGN Sixty-seven patients with advanced solid tu...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
I L Medintz J H Konnert A R Clapp I Stanish M E Twigg H Mattoussi J M Mauro J R Deschamps

The first generation of luminescent semiconductor quantum dot (QD)-based hybrid inorganic biomaterials and sensors is now being developed. It is crucial to understand how bioreceptors, especially proteins, interact with these inorganic nanomaterials. As a model system for study, we use Rhodamine red-labeled engineered variants of Escherichia coli maltose-binding protein (MBP) coordinated to the...

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