young children with history of maternal stress during pregnancy suffer from several neurological and psychological disorders in the childhood. the purpose of this study was to investigate the effect of maternal stress during pregnancy on the neural apoptosis in the newborns. pregnant wistar rats were divided into control and stress groups. stress was applied on the pregnant females from day 15 ...

brain areas implicated in the stress response include the amygdala, hippocampus and prefrontal cortex. neonatal stimulation of an animal by handling or by enhanced maternal care induces at adult age a decrease of the hypothalamo-pituitary adrenal (hpa) response to stressors, a decrease of anxiety in a novel environment, and neuroanatomical changes. in this present study we demonstrated that mat...

background & aim: women experience various changes in their transition into motherhood and feel stressed while facing new challenges in this period. high levels of stress may prevent mothers from realizing their maternal role. in this study, we aimed to explore the effects of training on the stress of primiparous mothers. methods:in this quasi-experimental intervention, 100 pregnant women were ...

BACKGROUND This study explores the differences in prenatal maternal expectations, coping resources and maternal stress between first time mothers of IVF twins and first time mothers of spontaneously conceived twins. The role of prenatal maternal expectations in the prediction of maternal stress was examined, as well as the mediating and moderating effect of coping resources on the association b...

Maternally-derived hormones in oocytes, such as glucocorticoids (GCs), play a crucial role in embryo development in oviparous taxa. In fishes, maternal stressor exposure increases circulating and egg cortisol levels, the primary GC in fishes, as well as induces oxidative stress. Elevated egg cortisol levels modify offspring traits but whether maternal oxidative stress correlates with circulatin...

OBJECTIVE Prenatal exposure to inappropriate levels of glucocorticoids (GCs) and maternal stress are putative mechanisms for the fetal programming of later health outcomes. The current investigation examined the influence of prenatal maternal cortisol and maternal psychosocial stress on infant physiological and behavioral responses to stress. METHODS The study sample comprised 116 women and t...

This study investigates whether maternal stress during pregnancy induces maternal and fetal hypothalamic paraventricular nucleus (PVN) neuronal activation and the effects of maternal stress on fetal hypothalamic and PVN brain-derived neurotrophic factor (BDNF) expression. Pregnant rats were exposed to three types of maternal stress with varying severity (restraint, forced walking and immobiliza...

There is evidence that the developmental trajectory of cortisol secretion in preterm infants is altered, with elevated basal cortisol levels observed postnatally through at least 18 months corrected age (CA). This alteration is possibly due to neonatal pain-related stress. High cortisol levels might contribute to greater risk of impaired neurodevelopment. Since maternal factors are important fo...

Animal models suggest that stress-induced hormonal changes in the mother during pregnancy lead to enduring changes in the fetus and empirical links between prenatal maternal stress and negative child development have been discerned repeatedly in human studies. But the role of heritable personality traits has received little attention in the latter work. The goal of the current study was to inve...

Background Borderline Personality Disorder (BPD) affects 0.9%-3.2% of adolescents, and more than 20% of inpatient adolescents. Life stress has been linked to BPD across the lifespan, and previous research in adults has linked BPD to dependent stress (i.e., stress induced by the individual). However, prior research has not examined dependent stress alongside BPD in adolescents. Additionally, the...