PURPOSE Leiomyosarcoma is a malignant neoplasm with smooth muscle differentiation. Little is known about its molecular heterogeneity and no targeted therapy currently exists for leiomyosarcoma. Recognition of different molecular subtypes is necessary to evaluate novel therapeutic options. In a previous study on 51 leiomyosarcomas, we identified three molecular subtypes in leiomyosarcoma. The cu...

Introduction Leiomyosarcoma (LMS) of the inferior vena cava (IVC) is a rare mesenchymal tumor originating from endothelial smooth muscle intima and account for about 1-2% all sarcomas soft tissue. The objective this article to show case IVC leiomyosarcoma, it?s resection reconstruction using ProxiCor. Case outlines We showed 65-year-old woman presented with abdominal pain mass in subhepatic spa...

abstract   soft tissue sarcomas of the oral cavity are uncommon malignancies those of smooth-muscle origin are extremely rare. leiomyosarcomas of the tongue are very rare. either surgery or radiation therapy with or without chemotherapy are the treatment modalities which improve prognosis. we are presenting a 32-year-old man with leiomyosarcoma of the lateral aspect of the oral tongue with neck...

Leiomyosarcoma of the uterus is a malignant tumor arising from the smooth muscle of the uterus. It is a rare tumor with an incidence as low as 2%-5% of all uterine malignancies. Besides the conventional type, one of the important variants includes the epithelioid leiomyosarcoma which is by itself a rare subtype of leiomyosarcoma. The precise diagnosis of leiomyosarcoma is essential since it has...

  Primary leiomyosarcoma of the broad ligament is a very rare, rapidly progressive and highly malignant gynecological tumor and only 16 cases have been reported in the literature. Here, presentation of leiomyosarcoma of the left broad ligament in a 26-years-old woman is reported. Clinical presentation and histological diagnosis is discussed. The patient has been treated surgically and remains...

Leiomyosarcoma is a malignant smooth-muscle tumour that is exceedingly rare in the head and neck region. Presenting signs and symptoms of leiomyosarcoma in the orofacial region are generally nonspecific. The tumour is commonly encountered as a slow growing, discreet firm, and non-ulcerated painless mass. We presented a case of massive leiomyosarcoma of the midface which might be the first leiom...

A 49-year-old woman with a distant history of uterine leiomyosarcoma underwent robotic-assisted laparoscopic partial nephrectomy for a 3.5 cm right renal mass, which was presumed to be a primary renal cell carcinoma. Surgical margins were negative, and the histologic analysis confirmed leiomyosarcoma. Uterine leiomyosarcoma is traditionally a locally aggressive disease with only rare reports of...

We report an unusual clinical presentation of renal leiomyosarcoma. A woman, who received renal transplant from her mother, was diagnosed to have leiomyosarcoma in the donated kidney. The mother was found to have a right upper lobe lung mass 10 years later, which was diagnosed as leiomyosarcoma. It is possible that the mother had primary leiomyosarcoma of the donated kidney with micrometastases...

Leiomyosarcoma may occur anywhere in the body but rarely occurs in the heart or great vessels. Leiomyosarcoma may be managed by surgical resection with or without chemotherapy or radiotherapy. Owing to the high rate of metastasis and poor prognosis, a definitive treatment modality for leiomyosarcoma has not yet been suggested. This case study reports the surgical management of the recurrent lei...

•Management of cervical leiomyosarcoma in pregnancy requires a multidisciplinary approach.•Ovarian preservation is preferred in young patients with early stage cervical leiomyosarcoma.•Routine lymphadenectomy in patients with early stage cervical leiomyosarcoma is not useful.