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Quantitative polymerase chain reactions (qPCR) based on real-time PCR constitute a powerful and sensitive method for the analysis of nucleic acids. However, in qPCR, the ability to multiplex targets using differently colored fluorescent probes is typically limited to 4-fold by the spectral overlap of the fluorophores. Furthermore, multiplexing qPCR assays requires expensive instrumentation and ...
A versatile approach for the rapid prototyping of microfluidic devices suitable for use with FT-IR spectroscopic imaging is introduced. Device manufacture is based on the direct printing of paraffin onto the surface of an infrared transparent substrate, followed by encapsulation. Key features of this approach are low running costs, rapid production times, simplicity of design modifications and ...
Plasma concentrations of orally administered methadone are reduced by the human immunodeficiency virus protease inhibitor combination ritonavir and lopinavir, but the mechanism is unknown. Methadone metabolism, clearance, and drug interactions have been attributed to CYP3A4, but this remains controversial. This investigation assessed the effects of acute (2 days) and steady-state (2 weeks) rito...
Pirkko J. Pussinen, Tiina Vilkuna-Rautiainen, Georg Alfthan, Timo Palosuo, Matti Jauhiainen, Lipopolysaccharide Severe Periodontitis Enhances Macrophage Activation via Increased Serum Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2004 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 Arterio...
Rohrer, Arnold von Eckardstein, Sabino Iliceto, Massimo Volpe, Thomas F. Lüscher and Elena Osto, Alexei Kouroedov, Pavani Mocharla, Alexander Akhmedov, Christian Besler, Lucia Receptor A Expression in Human Macrophages Prevents Foam Cell Formation by Reducing Scavenger β Inhibition of Protein Kinase C Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2008 American Heart Association, Inc...
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