نتایج جستجو برای: l. infantum

تعداد نتایج: 619367  

Journal: :Veterinary immunology and immunopathology 2009
Hamid Daneshvar Mohammad M Molaei Reza Malekpour Afshar Hosein Kamiabi Richard Burchmore Paul Hagan R Stephen Phillips

The clinicopathological changes following infection with an attenuated line of Leishmania infantum (L. infantum H-line) were evaluated in mixed breed dogs. Two groups of dogs were infected intravenously (i.v.) or intradermally (i.d.) with L. infantum H-line and two control groups were infected i.v. or i.d. with L. infantum wild-type (L. infantum WT). None of the dogs, which were infected i.v. o...

Journal: :Clinical and vaccine immunology : CVI 2012
Kevin W Bruhn Ron Birnbaum Jacquelyn Haskell Veena Vanchinathan Stephanie Greger Rupa Narayan Pei-Lin Chang Thu Anh Tran Suzanne M Hickerson Stephen M Beverley Mary E Wilson Noah Craft

There are currently no effective vaccines for visceral leishmaniasis, the second most deadly parasitic infection in the world. Here, we describe a novel whole-cell vaccine approach using Leishmania infantum chagasi promastigotes treated with the psoralen compound amotosalen (S-59) and low doses of UV A radiation. This treatment generates permanent, covalent DNA cross-links within parasites and ...

2011
Katrin Kuhls Mohammad Zahangir Alam Elisa Cupolillo Gabriel Eduardo M. Ferreira Isabel L. Mauricio Rolando Oddone M. Dora Feliciangeli Thierry Wirth Michael A. Miles Gabriele Schönian

Leishmania infantum (syn. L. chagasi) is the causative agent of visceral leishmaniasis (VL) in the New World (NW) with endemic regions extending from southern USA to northern Argentina. The two hypotheses about the origin of VL in the NW suggest (1) recent importation of L. infantum from the Old World (OW), or (2) an indigenous origin and a distinct taxonomic rank for the NW parasite. Multilocu...

A. Naghibi, G. Razmi, J. Khoshnegah S. Sabzavari,

Zoonotic visceral leishmaniasis is caused by Leishmania infantum (L. infantum),and its major reservoir hosts are domestic dogs, most of which are asymptomatic. This study aimed to detect L. infantum spp. in asymptomatic stray dogs by molecular and serological methods in Mashhad, Iran, during 2011-12. In this study, 94 asymptomatic stray dogs were randomly selected and their blood samples were c...

ژورنال: Medical Laboratory Journal 2017
Abouhosseini Tabari , Mohaddeseh, Ebrahimi, Mohammad Amin , Hosseini Farash , Bibi Razieh , Moghaddas, Elham, Nabavi Mousavi , Niki, Youssefi, Mohammad Reza ,

ABSTRACT          Background and Objectives: Due to adverse effects of pentavalent  antimonial  treatment of visceral leishmaniasis using herbal medicines has received a lot of attention. In this study, we evaluated inhibitory activity of Pelargonium roseum essential oil on growth of Leishmania infantum promastigotes, and compared it with that ...

2013
Mauro Maciel de Arruda Fabiano Borges Figueiredo Fernanda Alvarenga Cardoso Roberto Mitsuyoshi Hiamamoto Júlia Cristina Macksoud Brazuna Maria Regina Fernandes de Oliveira Elza Ferreira Noronha Gustavo Adolfo Sierra Romero

BACKGROUND American visceral leishmaniasis is caused by the protozoan Leishmania infantum. Dogs are the main reservoirs in the domestic transmission cycle. The limited accuracy of diagnostic tests for canine leishmaniasis may contribute to the lack of impact of control measures recommended by the Brazilian Ministry of Health. The objective of this study was to estimate the accuracy of two enzym...

2017
Bibi Razieh HOSSEINI FARASH Mehdi MOHEBALI Bahram KAZEMI Homa HAJJARAN Behnaz AKHOUNDI Reza RAOOFIAN Abdolmajid FATA Majid MOJARRAD Mohammad Kazem SHARIFI-YAZDI

Background Visceral leishmaniasis (VL) caused by Leishmania infantum is the most severe form of leishmaniasis in Iran, which causes a high mortality rate in the case of inaccurate diagnosis and treatment. This study aimed to clone of K26 gene from Iranian strain of L. infantum and register the sequencing results in Genbank to facilitate the preparation a new K26 antigen for the detection of L. ...

2017
Valéria da Costa Oliveira Viviane Cardoso Boechat Artur Augusto Velho Mendes Junior Maria de Fátima Madeira Luiz Claudio Ferreira Fabiano Borges Figueiredo Monique Paiva Campos Francisco das Chagas de Carvalho Rodrigues Raquel de Vasconcellos Carvalhaes de Oliveira Maria Regina Reis Amendoeira Rodrigo Caldas Menezes

Zoonotic visceral leishmaniasis is caused by the protozoan Leishmania infantum and little is known about the occurrence and pathogenesis of this parasite in the CNS. The aims of this study were to evaluate the occurrence, viability and load of L. infantum in the CNS, and to identify the neurological histological alterations associated with this protozoan and its co-infections in naturally infec...

Journal: :Journal of vector borne diseases 2010
H Mahmoudzadeh-Niknam F Abrishami M Doroudian M Moradi M H Alimohammadian P Parvizi

BACKGROUND & OBJECTIVES Kala-azar is the visceral and most severe form of leishmaniasis that leads to death if untreated. The causative agents of visceral leishmaniasis (VL) are members of Leishmania (L.) donovani complex which includes L. chagasi and L. infantum. Genome sequences have raised the question whether L. chagasi and L. infantum are synonymous or different. This question has importan...

2015
Kézia Peres GUALDA Lílian Mathias MARCUSSI Herintha Coeto NEITZKE-ABREU Sandra Mara Alessi ARISTIDES Maria Valdrinez Campana LONARDONI Rosilene Fressatti CARDOSO Thaís Gomes Verzignassi SILVEIRA

Leishmania infantum causes visceral leishmaniasis (VL) in the New World. The diagnosis of VL is confirmed by parasitological and serological tests, which are not always sensitive or specific. Our aim was to design new primers to perform a Polymerase Chain Reaction (PCR) for detecting L. infantum. Sequences of the minicircle kinetoplast DNA (kDNA) were obtained from GenBank, and the FLC2/RLC2 pr...

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