objective(s) leishmania can lead to a broad spectrum of diseases, collectively known as leishmaniasis. the a2 gene/ protein family could be one of the most eligible candidate factors of virulence in visceral leishmaniasis (vl). the previous results confirmed that in leishmania infantum, several a2 proteins are abundantly expressed by the amastigote, but not the promastigote stage. as there are ...

b a ckground: cutaneous leishmaniasis (cl) represents the most frequent vector borne parasitoses in iran. the ob-jective of this study was to determine the epidemiological features of cl including human infection and the reservoir host in the city of bushehr, bushehr province, iran during 2010–2011. m e t hods: studies on human infection was carried out on 2962 school children aged 7–14 years o...

leishmaniasis is caused by parasitic protozoa of the genus leishmania. cutaneous leishmaniasis (cl) is a complex disease with wide spectrum of clinical manifestations. in order to identify leishmania species causing cl in isfahan by a definite molecular technique (pcr method), this study was undertaken over 2010- 2011. 124 patients with suspicious lesion of leishmaniasis and positive direct sme...

background: leishmania, needs to detoxify the macrophage derived potent peroxides (h2o2). tryparedoxin path­way contains tryparedoxin peroxidase (tsa or tryp). the aim of the study was to detect the full-length gene se­quence and its encoded protein of the lmtryp6 gene (eu251502), and comparison the gene sequence with lmtryp6 (lmjf15.1140), another previously reported member of this gene family...

Objective(s) Leishmania can lead to a broad spectrum of diseases, collectively known as leishmaniasis. The A2 gene/ protein family could be one of the most eligible candidate factors of virulence in visceral leishmaniasis (VL). The previous results confirmed that in Leishmania infantum, several A2 proteins are abundantly expressed by the amastigote, but not the promastigote stage. As there are...

the immune responses of mice immunized with ovalbumin (ova) together with killed l. major (klm) promastigotes as adjuvant were studied. three doses (5 × 107, 1 × 108 and 2 × 108) of klm combined with ova (100 mg) were injected into the groups of c57bl/6 mice. bcg and complete freund’s adjuvant (cfa) were used as control adjuvants. lymphocyte proliferation and antibody titers were determined, an...