Objective: The study is centered on formulation and evaluation of low viscosity metronidazole gel with varying amount Carbopol. Methods: Formulations (F1, F2 F3) Metronidazole in form were done amounts Prepared gels inspected for surface pH, viscosity, spreadability, antimicrobial susceptibility, drug content percentage, vitro process release, release kinetics stability testing. Findings: Formu...

The objective of the current investigation is to reduce dosing frequency and improve patient compliance by designing and systematically evaluating sustained release microballoons of Propranolol hydrochloride. An antihypertensive drug, Propranolol hydrochloride, is delivered through the microparticulate system using ethyl cellulose as the controlled release polymer. Microballoons were developed ...

The objective of the current investigation is to reduce dosing frequency and improve patient compliance by designing and systematically evaluating sustained release microspheres of Glipizide. An anti-diabetic drug, Glipizide, is delivered through the microparticulate system using ethyl cellulose as the controlled release polymer. Microspheres were developed by the emulsion solvent diffusion-eva...

The objectives of the study were to formulate hydroxypropyl methyl cellulose-based controlled release matrix tablets for theophylline with varying drug:polymer ratios (1:1 and 1:2) and differing tablet hardness (5, 6 and 7 kg/cm(2)), and to evaluate the tablet's physico-chemical properties such as hardness, uniformity of weight, friability, drug content and in vitro drug release. Initially, gra...

Purpose of present study was to develop eight formulations chlorpheniramine (CPM) niosomes according 23 factorial design, characterise on the basis various evaluation tests, i.e. in vitro drug release, SEM, FTIR, TGA and release kinetics, optimise formulation data, formulate gel optimised dispersion, perform vivo histopathological using dispersion rabbits. Here, N3 having low level cholesterol ...