fibrillation is a hazardous phenomenon in cardiac muscle and so any new work towards the understanding of this process is important to the development of new methods in diagnosis and therapy. in this work we have used surface and intra cardiac ecgs of patients with chronic atrial fibrillation (af). by means of the blind source separation (bss) algorithm, which is a well-known method in signal p...

Identified neurons in different animals express ionic currents at highly variable levels (population variability). If neuronal identity is associated with stereotypical function, as is the case in genetically identical neurons or in unambiguously identified individual neurons, this variability poses a conundrum: How is activity the same if the components that generate it-ionic current levels-ar...

Description of Procedure or Service Iontophoresis is a method of transdermal local drug delivery using electrical current. A charged, ionic drug is placed on the skin with an electrode of the same charge, allowing direct current to drive the drug into the skin. Ultrasound transdermal delivery involves the use of ultrasonic energy to enhance delivery of solutes either simultaneously or via pre-t...

Bulk ionic conductivity, Ionic Thermal Current (I.T.C.), and Thermally Stimulated Polarization Current (T.S.P.C.) studies are reported for the system Bal-,LaXF2+, (0.12 x loe2 < x < 0.45). The obtained results are illustrative for the compositional dependence of the ionic conductivity of anion-excess solid solutions. For small solute content simple associates as well as free mobile fluoride int...

The peptide omega-agatoxin-IIIA (omega-Aga-IIIA) blocks ionic current through L-type Ca channels in guinea pig atrial cells without affecting the associated gating currents. omega-Aga-IIIA permits the study of L-type Ca channel ionic and gating currents under nearly identical ionic conditions. Under conditions that isolate L-type Ca channel currents, omega-Aga-IIIA blocks all ionic current duri...