introduction: postoperative pain is an acute pain related to size and site of operation, patient's psychologic and physiological condition, degree of manipulation and damage of tissues. pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. administration of opioids is one of the common techniques for postoperative pain management, but com...

Intravenous lidocaine administration produces an analgesic effect in various pain states, such as neuropathic and acute pain, although the underlying mechanisms remains unclear. Here, we hypothesized that intravenous lidocaine acts on spinal cord neurons and induces analgesia in acute pain. We therefore examined the action of intravenous lidocaine in the spinal cord using the in vivo patch-clam...

background: decreasing intraocular pressure (iop) and preventing the iop rising during cataract surgery, is one of the most important factors in successful cataract surgery. this study was conducted to investigate the effects of intravenous lidocaine on iop in cataract surgery under sedation. methods: the study was a double blind controlled trial which firstly, the patient’s iop was measured. t...

background: propofol is a widely used intravenous anesthetic drug. one of its side effects is pain during injection. we investigate the effects of intravenous ondansetron, lidocaine, and their combination on pain reduction of intravenous propofol. methods: eighty eight women with asa class (american society of anesthesiologists) classification i-ii patients undergoing elective gynecologic surge...

This study aimed to determine if intravenous lidocaine infusion reduces postoperative pain intensity following laparoscopic fundoplication surgery and to also validate the safety of intravenous lidocaine at the dose tested. This was an equally randomized, double-blind, placebo-controlled, parallel-group, single center trial. Adult patients undergoing laparoscopic fundoplication were recruited. ...

BACKGROUND The analgesic effect of perioperative low doses of intravenous lidocaine has been demonstrated after abdominal surgery. This study aimed to evaluate whether a continuous intravenous low-dose lidocaine infusion reduced postoperative pain and modified nociceptive pain threshold after total hip arthroplasty. METHODS Sixty patients participated in this randomized double-blinded study. ...

BACKGROUND AND OBJECTIVES Most patients undergoing surgery experience moderate to severe pain, indicating the need to improve the anesthetic technique. Intravenous lidocaine has been widely used in the treatment of chronic pain. The objective of this report was to review the use of intravenous lidocaine for postoperative analgesia. CONTENTS The pharmacologic aspects and mechanism of action of...

objective: to compare the efficacy of intravenous and intraperitoneal injection of lidocaine and normal saline in relieving postoperative pain after elective abdominal hysterectomy. materials and methods: for this double-blind randomized controlled study 109 patients undergoing elective abdominal hysterectomy were randomly allocated to three groups :1) iv group (intravenous injection group) rec...

Endoscopic submucosal dissection (ESD) is an advanced therapy for early gastric neoplasm and requires sedation with adequate analgesia. Lidocaine is a short-acting local anesthetic, and intravenous lidocaine has been shown to have analgesic efficacy in surgical settings. The aim of this study was to assess the effects of intravenous lidocaine on analgesic and sedative requirements for ESD and p...