نتایج جستجو برای: interferon gamma (ifn
تعداد نتایج: 179244 فیلتر نتایج به سال:
Abstract Background and objectives: Interferon-Gamma and interferon Gamma receptor (IFNγ ⁄ IFNγR1) are the main genes associated with susceptibility to tuberculosis. We aimed at studying on interferon-Gamma Gene polymorphism(- 56 C/T) in people suffered from tuberculosis (TB). Material and Methods: In this case-control study, the subjects were 62 individuals with TB and 74 hea...
Background: Hepatitis C virus (HCV) is a worldwide health problem, which associated with cirrhosis and hepatocellular carcinoma. Interferon-α and Ribavirin are only acceptable treatment regimen for these patients. These regimen are effective only on 50% of the patients. The aim of this study was to evaluate the response to treatment with interferon gamma gene polymorphism in patients with...
Background: As a T helper type 1 (Th1) derived cytokine, Interferon gamma (IFN-γ) is an important regulator of inflammatory immune responses. Furthermore, IFN-γ plays an essential role in defense against tumors and intracellular pathogens. This study was designed to assess the pattern of IFN-γ production in human leukemic (Jurkat and Molt-4) T cell lines in vitro. Methods: Ju...
Objective: The interleukin-12/interferon-γ (IL-12/IFN-γ) pathway is the most validated cytokine regulating Mycobacterium tuberculosis infection. role of IL-12/IFN-γ axis in protecting against (TB) exhibited people having mutations genes encoding these cytokines. We aimed to study serum levels IL-12 and IFN-γ pediatric their correlation with clinical microbiological features. Material Methods: A...
interleukin-4 (il-4) is produced by t-helper cells type 2 (th2) and induces ige synthesis. t-helper cells type 1 (th1) produce interferon-gamma (ifn-gamma) which suppresses th2 and reduces il-4 induced ige production. in this :;tudy , we demonstrated that the levels of specific ige in the serum of atopic children (n=20) were elevated while il-4 production was increased and ifn-gamma secretion w...
Background: Obesity is one of the most serious health problems associated with inflammation. It has been found that functional and resistance physical activities improve obesity and inflammation. The aim of this study was to investigate the effect High-intensity Functional training (HIFT) and Circuit resistance training (CRT) on serum levels of the pro-inflammatory factor interferon gamma (IFN-...
Interferon (IFN) production by human peripheral lymphocytes stimulated with M. pneumoniae was investigated. The hydrogen peroxide released from M. pneumoniae was responsible for the induction of IFN from lymphocytes, since horseradish peroxidase inhibited the IFN production and abrogated the activity of IFN production in the supernatant of M. pneumoniae. The antiserum neutralizing IFN alpha and...
The administration of interferon has improved the antiviral and immunomodulatory abilities piglets, which is conductive to prevention potential diseases or delay appearance clinical symptoms. This study aimed evaluate effects from recombinant interferon-alpha (IFN-α) on daily care piglets. results were compared a Chinese herbal drug that was shown increase serum levels. In addition, routes oral...
Abstract Background: The annual Hajj pilgrimage to Holy Mecca, brings over two million people together in a small confined area through the world. Respiratory illnesses are the most common afflictions during this ceremony presenting as various clinical syndromes. Several microbiologic, Sero-epidemiologic and Immunologic studies have revealed that most of these syndromes are caused by viral i...
Prior to the production of human gamma interferon using recombinant DNA technology, it had been producedmainly upon mitogenic induction of lymphocytes in very low amounts, which evidently hamperedits characterization and its medical applications. The recombinant gamma interferons produced in largerquantities in prokaryotic systems retain their biological activities, and can be...
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