zhumeria majdae is a rare an endemic medicinal plantspecies grown wild in iran. the hydro distilled essential aerial part oil of z. majdae analysed by gc–ms. thirty-one compounds representing 95.36% of the aerial part oil, respectively, were identified, of which linalool (48.14%), camphor (20.71%), limonene (4.83%), trans-linalool oxide (2.69%), 3-octanone (2.34%), terpinene-4-ol (2.30%), camph...

introduction: the aim of this study was to compare the antibacterial effect of persian green tea extract (gte) and 2.5% sodium hypochlorite (naocl) against enterococcus faecalis ( e. faecalis ) as an intracanal irrigant. methods and materials: thirty freshly extracted teeth were instrumented and sectioned into mesial and distal segments. the specimens were put into wells containing 2 ml of e. f...

We investigated the regeneration of cardiac lymphatic vessels and capillaries in the infarcted myocardiac zones after acute myocardial infarction in rats. The anterior descending artery of the heart was ligated for infarction and both immunohistochemistry and immunofluorescence were used to detect pathological changes of lymphatic vessels in infarcted zone (IZ), infarcted margin zone (MZ) and r...

Neuronal production in the midbrain-hindbrain domain (MH) of the vertebrate embryonic neural tube depends on a progenitor pool called the ;intervening zone' (IZ), located at the midbrain-hindbrain boundary. The progressive recruitment of IZ progenitors along the mediolateral (future dorsoventral) axis prefigures the earlier maturation of the MH basal plate. It also correlates with a lower sensi...

β-adrenergic receptor (β-AR) blockers may be administered during acute myocardial infarction (MI), as they reduce energy demand through negative chronotropic and inotropic effects and prevent ischemia-induced arrhythmogenesis. However, the direct effects of β-AR blockers on ventricular electrophysiology and intracellular Ca2+ handling during ischemia remain unknown. Using optical mapping of tra...

We report the antibacterial activity of the plant extracts and three previously isolates known compounds viz., nonacosane-10-ol (alcohol), 23a-homostigmast-5-en-3ß-ol (homolog of β-sterol) and cisand trans-prtopinium (alkaloid) of Fumaria parviflora Lam (Fumariaceae) for the first time. Plant extracts and pure compounds were in vitro assessed against seven clinical Gram (-) and Gram (+) bacteri...

Changes in the ventricular diastolic excitability threshold following occlusion of the left anterior descending coronary artery (LAD) were studied in open-chest anesthetized dogs by using a new automatic threshold-following pacemaker (ATFP). The ATFP measures the diastolic excitability threshold by successively decreasing the duration of regularly occurring pacing stimuli until the ventricle fa...

We consider the indi↵erence-zone (IZ) formulation of the ranking and selection problem with independent normal samples. In this problem, we must use stochastic simulation to select the best among several noisy simulated systems, with a statistical guarantee on solution quality. Existing IZ procedures sample excessively in problems with many alternatives, in part because loose bounds on probabil...

Background and objectives: Trigonella tehranica (Leguminosae) is an indigenous plant in northern regions of Iran. There were many reports about antimicrobial activity of other specious of this genus; therefore, the aim of present study was investigation of chemical compounds and antimicrobial activities of T. tehranica essential oils for the first time. <stron...

During development, cortical interneurons generated from the ventral telencephalon migrate tangentially into the dorsal telencephalon. Although Achaete-scute family bHLH transcription factor 1 (Ascl1) plays important roles in the developing telencephalon, whether Ascl1 regulates tangential migration remains unclear. Here, we found that Ascl1 promoted tangential migration along the ventricular z...